Center for Visual and Neurocognitive Rehabilitation

视觉和神经认知康复中心

• 批准号: 10268983
• 负责人: A. M. Barrett
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-10-01 至 2023-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10268983
• 关键词: Age related macular degeneration; Aging; Alzheimer' s Disease; Animal Model; Animals; Biomedical Engineering; Brain Diseases; Caring; Clinical Trials; Communities; Disease; Doctor of Philosophy; Ensure; Extramural Activities; Fostering; Funding; Goals; Grant; Health; Human; Institutes; Intervention; Joints; Literature; Mentorship; Mission; Molecular Biology; Neural Retina; Neurocognitive; Neurocognitive Deficit; Neurology; Ophthalmology; Patients; Personal Satisfaction; Physical Exercise; Physical Medicine; Recovery of Function; Rehabilitation therapy; Research; Research Personnel; Retinal Degeneration; Scientist; Services; Sleep; Stroke; System; Technology; Testing; Time; Training; Universities; Veterans; Visual; Visual impairment; Wolves; base; career development; design; experience; healthy aging; imaging facilities; meetings; military veteran; neural repair; neuroimaging; outreach; preclinical study; prevent; programs; psychoeducational; recruit; rehabilitation research; rehabilitation strategy; repetitive transcranial magnetic stimulation; research and development; research study; synergism; telerehabilitation

The mission of the Atlanta VAMC Rehabilitation Research and Development Center for Visual and Neurocognitive Rehabilitation (CVNR) is to foster the best possible health and well-being of Veterans through uniquely synergistic research studies targeting disorders impacting visual and/or neurocognitive function. Our Center's organization is designed to catalyze synergies amongst collaborating CVNR researchers and with scientist and clinician affiliates to maximize and accelerate tangible benefits for Veterans' health. The Internal Steering Group is the hub of CVNR operational decisions and comprises Krish Sathian, MD, PhD (Executive Director); Bruce Crosson, PhD (Executive Associate Director); Machelle Pardue, PhD (Associate Director for Scientific Projects); Steven Wolf, PT, PhD (Associate Director for Training), Patricia Griffiths, PhD (Assistant Director for Outreach); Keith McGregor, PhD (Career Development Awardees' Representative); and Lisa Calas (Administrative Officer). The CVNR has three Research Programs: (A) Retinal & Neural Repair, (B) Visual Rehabilitation, and (C) Neurocognitive Rehabilitation. The CVNR's emphasis is on highly collaborative research efforts that straddle and integrate across the Programs. To this end, we plan three Integrative Projects that each draw on expertise and ideas from multiple Programs: (1) Physical exercise to prevent progression of age-related macular degeneration in Veterans; (2) Repetitive transcranial magnetic stimulation in aging and stroke: mechanistic pre-clinical studies using animal models; and (3) Making a psycho-educational tele- rehabilitative sleep intervention accessible for Veterans with visual impairment and their cohabitating care- partners. Each of these projects will be funded by the CVNR for an initial 2-year period, with the goal of seeding extramurally funded research by that time. In subsequent years, additional Integrative Projects will be funded after competitive review. Note that the activity of CVNR investigators is not limited to these Integrative Projects; each investigator is involved in multiple other projects that will be further enriched by the experiences and results of the Integrative Projects. The CVNR will also fund a set of Cores to provide services to investigators. Three of these are ongoing: a Neuroimaging Core directed by Dr. Crosson, a Molecular Biology Core directed by Dr. Boatright, and an Administrative Core directed by Ms. Calas. Two additional Cores will be added in year 3 of the new grant cycle: a Physical Exercise Core directed by Dr. Nocera and a Tele-rehabilitation Core co-directed by Drs. Griffiths and McGregor and Mr. Ross. The CVNR has strong ties with local affiliates, including the Birmingham-Atlanta GRECC; Emory University, particularly its imaging centers, its Alzheimer's Disease Research Center, and its Departments of Neurology, Ophthalmology and Rehabilitation Medicine; Georgia Institute of Technology; the joint Biomedical Engineering Department of Emory and Georgia Tech; and Georgia State University. Our research findings will be shared through the national network of Centers, disseminated in the scientific literature and at scientific meetings, presented to VA and other clinicians locally and nationally, and distilled into educational programs for Veterans, other consumer groups, and the community. The CVNR is committed to capacity building by recruiting trainees as well as junior and senior investigators into the VA system and providing trainees with outstanding mentorship to ensure the continued vitality of rehabilitation research.

亚特兰大VAMC康复研究与发展中心的使命 神经认知康复（CVNR）是为了促进退伍军人的最佳健康和福祉 通过独特的协同研究研究，针对影响视觉和/或神经认知的疾病 功能。我们中心的组织旨在催化CVNR协作中的协同作用 研究人员以及科学家和临床医生分支机构，以最大化和加速切实的好处 退伍军人的健康。内部转向组是CVNR操作决策的枢纽，并包括 医学博士Krish Sathian（执行董事）； Bruce Crosson博士（执行副主任）；马切尔 Pardue，博士（科学项目副总监）；史蒂文·沃尔夫（Steven Wolf），PT，博士学位（副主任 培训），Patricia Griffiths博士（外展助理主任）； Keith McGregor博士（职业 发展获奖者的代表）；和丽莎·卡拉斯（Lisa Calas）（行政官）。 CVNR有三个研究计划：（a）视网膜和神经修复，（b）视觉康复， （c）神经认知康复。 CVNR的重点是高度协作的研究工作 跨程序跨和集成。为此，我们计划每个绘制的三个集成项目 关于多个计划的专业知识和想法：（1）体育锻炼以防止与年龄有关 退伍军人的黄斑变性； （2）衰老和中风中的重复经颅磁刺激： 使用动物模型的机械临床前研究； （3）制作心理教育 有视觉障碍的退伍军人及其同居的护理可供康复睡眠干预措施 合作伙伴。这些项目中的每一个都将由CVNR资助最初的2年，目的是 到那时，播种外部资助的研究。在随后的几年中，其他集成项目将 在竞争性审查后获得资助。请注意，CVNR研究人员的活动不限于这些 综合项目；每个调查员都参与了其他多个项目，这些项目将进一步丰富 综合项目的经验和结果。 CVNR还将资助一组核心，为调查人员提供服务。其中三个是 正在进行的：由Crosson博士执导的神经影像核心，该核心是由Boatright博士执导的分子生物学核心 以及由卡拉斯女士执导的行政核心。新的第三年将增加两个核心 赠款周期：由Nocera博士执导的体育锻炼核心和由Tele-Grearbilitation Core共同指导的 博士。格里菲斯（Griffiths）和麦格雷戈（McGregor）和罗斯先生。 CVNR与当地分支机构有着密切的联系，包括 伯明翰 - 阿特兰塔格雷克；埃默里大学，尤其是其成像中心，阿尔茨海默氏病 研究中心及其神经病学，眼科和康复医学部门；乔治亚州 技术研究院；埃默里和佐治亚理工学院联合生物医学工程系；和 佐治亚州立大学。 我们的研究发现将通过国家中心网络共享，并在 科学文学和科学会议，向弗吉尼亚州和其他临床医生介绍了本地和全国的其他临床医生 并提炼为退伍军人，其他消费者群体和社区的教育计划。这 CVNR致力于通过招募受训者以及初级和高级调查员来建设能力 进入VA系统，并为学员提供出色的指导，以确保持续的活力 康复研究。