Wyoming Sensory Biology COBRE

怀俄明州感官生物学 COBRE

• 批准号: 10216275
• 负责人: Qian-Quan Sun
• 金额: $ 200.41万
• 依托单位: UNIVERSITY OF WYOMING
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10216275
• 关键词: Address; Antibodies; Area; Basic Science; Behavior; Biology; Biomedical Research; Centers of Research Excellence; Collaborations; Core Facility; Development; Equilibrium; Faculty; Fostering; Functional disorder; Funding; Future Teacher; Goals; Image; Impairment; Interdisciplinary Study; Journals; Laboratory Research; Leadership; Learning Disorders; Link; Manuscripts; Mentors; Methodology; Microscopy; Mission; Modality; Molecular; Molecular Analysis; National Institute on Deafness and Other Communication Disorders; Obesity; Peer Review; Physiological; Process; Publications; Publishing; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Role; Sensory; Sensory Disorders; Sensory Process; System; Training; Translational Research; United States; United States National Institutes of Health; Universities; Vision; Wyoming; chronic pain; experience; interest; multidisciplinary; operation; recruit; sensory neuroscience; sensory stimulus; sensory system; success; visual learning; web site

Abstract The primary mission of the Wyoming Sensory Biology COBRE (SBC) is to foster and conduct high-quality scientific research that advances the understanding of our sensory systems and disorders related to them. SBC will accomplish its mission through the augmentation and strengthening of UW's institutional biomedical research capacity. This will be accomplished through building a critical mass of investigators whose research interests center around sensory processes at the molecular, cellular, physiological and system levels. SBC will promote the competitiveness of the core investigators by providing mentoring, training, collaboration and research support. The SBC will be led by the PI with the help of an excellent group of additional mentors. The PI is an established sensory system investigator with expertise that is germane to the research theme of the center, has an active research laboratory, has obtained peer-reviewed funding and has extensive administrative leadership and mentoring experience. The SBC is comprised of the Administration Core, the Integrated Microscopy Core (IMcore), and four interrelated research projects. As a whole, the SBC will support four new junior investigators and four future faculty hires that are committed to the SBC, during the five years of the COBRE funding. The Center will comprise a multi-disciplinary team of investigators with expertise across multiple sensory modalities, including somatosensation, chemosensation, and vision. The SBC investigators' research portfolios demonstrate a balance of basic and translational research across multiple fields. The five-year goals of the SBC are the following: 1. Establish a multi- disciplinary center that brings together investigators with expertise in diverse areas of sensory neuroscience and experimental methodology, and fosters collaborations to address key issues in sensory function and dysfunction. 2. Support the projects of junior investigators by providing strong mentoring and guidance to help them obtain independent funding and professional success. 3. Grow the SBC in both size and scope through the recruitment of new faculty, as described in the Institutional Commitment, and fostering multi-disciplinary research among current UW faculty, respectively. 4. Build the required research infrastructure by expanding the capabilities of the Microscopy Core. 5. Advance our understanding of the development and function of sensory systems and their dysfunctions. Successful operation of the Center is expected to achieve the following milestones within the initial five years of funding: successful expansion of a state-of-the-art imaging and microscopy core facility, all four Project Leaders successfully competing for R01-level funding; four to six new or early-stage investigators added to the Center; two to four new mentors added (including Project Leaders who recently graduated from COBRE support); and at least 20 manuscripts accepted for publication or published in reputable peer-reviewed journals.

抽象的 怀俄明州感觉生物学鞋底（SBC）的主要任务是促进和进行 高质量的科学研究，以了解我们的感觉系统和 与他们有关的疾病。 SBC将通过增强来完成其使命 加强UW的机构生物医学研究能力。这将完成 通过建立大量的调查人员的研究兴趣围绕感官的兴趣 分子，细胞，生理和系统水平的过程。 SBC将促进 核心调查人员提供指导，培训，协作和 研究支持。 SBC将由PI领导，借助一组出色的额外 导师。 PI是一位知名的感官系统调查员，具有专业知识，这是如此 该中心的研究主题具有活跃的研究实验室，已获得同行评审 资金，拥有广泛的行政领导和指导经验。 SBC是 由管理核心，集成显微镜核心（IMCORE）和四个组成 相互关联的研究项目。总体而言，SBC将支持四名新的初级调查员和 在毛绒的五年中，致力于SBC的四名未来教师雇用 资金。该中心将组成一个跨学科的调查员团队，具有专业知识 多种感觉方式，包括体质，化学敏感和视力。 SBC 研究人员的研究组合表明了基本和转化研究的平衡 跨多个字段。 SBC的五年目标如下：1。 纪律中心将调查人员汇集到感官各个领域的专业知识 神经科学和实验方法，并促进了协作以解决关键问题 感觉功能和功能障碍。 2。通过提供支持初级调查人员的项目 强大的指导和指导，以帮助他们获得独立的资金和专业 成功。 3。通过招募新教师的规模和范围增长SBC 在机构承诺中描述，并在 UW当前的教师。 4。通过扩展来构建所需的研究基础架构 显微镜核心的功能。 5。提高我们对发展的理解和 感觉系统及其功能障碍的功能。中心成功操作是 预计将在最初的五年内实现以下里程碑：成功 扩展最先进的成像和显微镜核心设施，这四个项目领导者 成功争夺R01级资金；四到六个新的或早期的调查人员添加了 到中心；添加了两到四位新导师（包括最近毕业的项目领导者 来自毛线支撑）；至少有20份手稿被接受或发表 信誉良好的同行评审期刊。