HIV/AIDS Clinical Trials Unit (CTU) COVID-19 Admin Supplement

HIV/AIDS 临床试验单位 (CTU) COVID-19 管理补充资料

• 批准号: 10166401
• 负责人: Joseph J Eron
• 金额: $ 60万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-01 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166401
• 关键词: 2019-nCoV; AIDS prevention; AIDS/HIV problem; Address; Adherence; Adult; Agriculture; Area; Back; Belgium; COVID-19; COVID-19 pandemic; Caring; Cessation of life; Childhood; China; Clinic; Clinical; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical Trials Unit; Color; Communication; Communities; Contact Tracing; Containment; Coronavirus; Country; County; Data; Detection; Diagnosis; Diagnostic; Disease; Disease Outbreaks; Doctor of Philosophy; Emerging Communicable Diseases; Ensure; Equipment; Evaluation; Farming environment; Finland; General Population; Geography; Germany; Goals; HIV; HIV Infections; Health; Healthcare; Home environment; Hospitalization; Human; Incidence; Individual; Industry; Infection; Infection Control; Infrastructure; Institutes; Laboratories; Leadership; Life; Living Standards; Malawi; Meat; Modeling; Molecular; National Institute of Allergy and Infectious Disease; North Carolina; Performance; Pharmacy facility; Planets; Plants; Play; Population; Populations at Risk; Positioning Attribute; Prevention; Prevention strategy; Principal Investigator; Protocols documentation; Public Health; Quarantine; Reporting; Research; Resources; Role; Rural; Senior Scientist; Site; Social Distance; South Korea; Southeastern Asia; Southern Africa; Structure; Taiwan; Tennessee; Testing; Therapeutic; Time; Unemployment; United States National Institutes of Health; Universities; Vaccines; Vietnam; Virus; Work; authority; clinical research site; data management; experience; global health; improved; innovation; microbicide; operation; pandemic disease; preservation; prevent; quality assurance; racial and ethnic disparities; response; rural area; rural counties; screening; transmission process; urban area

Project Summary/Abstract The University of North Carolina (UNC) Global HIV Clinical Trials Unit (CTU) has a well established track record of high-quality, innovative clinical research, strong scientific leadership (both in and outside the NIH HIV/AIDS Networks), and access to critically important infected and at-risk populations in the Southeastern US, Southeast Asia and in Southern Africa. Drawn from a diverse team of clinical innvestigators spanning two continents, our is led by experienced principal investigators (Joseph Eron MD and Mina Hosseinipour MD) and will support all 5 NIH HIV Clinical Trials Networks: Adult Therapeutic Strategies, Strategies to Address HIV and HIV- associated Infections in Pediatric and Maternal Populations, Integrated HIV Prevention Strategies, Microbicide Strategies, and Vaccine Strategies to Prevent HIV Infection. The Clinical Research Sites (CRS) include Chapel Hill CRS led by David Wohl MD (Adult Therapeutic Strategies, Integrated Prevention, Microbicide and Vaccine), Greensboro CRS led by Cornelius Van Dam MD PhD (Adult Therapeutic Strategy and Integrated Prevention), Malawi CRS led by Lameck Chinula MD (all 5 Networks) and Vietnam (protocol specific site) led by Vivian Go. Supporting this leadership is a well-organized research team, comprising global experts and site collaborators who will work to execute the network scientific agendas. The CTU has also assembled a diverse group of senior scientists and public health officials to serve on our Scientific and Strategic Advisory Group. The CTU administration incorporates a highly organized structure that will be responsive to our experienced research teams across the CRS and will provide ongoing evaluation to ensure optimal performance and efficiency. The CTU is supported by state-of-the-art communications and outstanding laboratory, pharmacy, quality assurance, data management and regulatory support. With its robust administrative framework, the UNC Global HIV CTU is optimally positioned to provide scientific leadership and clinical trials infrastructure to advance the field of agenda of the NIAID HIV networks and emerging infectious disease such as the SARS-CoV-2 pandemic.

项目摘要/摘要 北卡罗来纳大学（UNC）全球艾滋病毒临床试验单元（CTU）有一个井 建立的高质量，创新临床研究，强大的科学领导力的往绩 （在NIH艾滋病毒/艾滋病网络内外），并获得至关重要的感染和 美国东南亚，东南亚和南部非洲的高风险人口。从 我们的临床创新者团队跨越了两个大洲，我们的领导是经验丰富的 首席调查员（Joseph Eron MD和Mina Hosseinipour MD）将支持所有5 NIH HIV临床试验网络：成人治疗策略，解决HIV和HIV-的策略 小儿和母体种群中的相关感染，综合艾滋病毒预防 防止艾滋病毒感染的策略，微生物策略和疫苗策略。临床 研究地点（CRS）包括由大卫·沃尔（David Wohl）领导的教堂山CR（成人治疗 Cornelius领导的Greensboro CRS策略，预防综合，杀生和疫苗） Van Dam MD博士（成人治疗策略和综合预防），马拉维CRS Lameck Chinula MD（所有5个网络）和越南（协议特定地点）由Vivian GO领导。 支持这一领导的是一个组织良好的研究团队，包括全球专家和网站 将努力执行网络科学议程的合作者。 CTU也有 组建了一群高级科学家和公共卫生官员，为我们服务 科学和战略咨询小组。 CTU管理高度合并 有组织的结构将对CRS的经验丰富的研究团队做出响应 并将提供持续的评估以确保最佳性能和效率。 CTU是 在最先进的通信和出色的实验室，药房，质量的支持下 保证，数据管理和监管支持。凭借其强大的行政框架， UNC全球HIV CTU在提供科学领导和临床方面处于最佳状态 试验基础设施以推进NIAID HIV网络和新兴的议程领域 传染病，例如SARS-COV-2大流行。