Clinical Core

临床核心

• 批准号: 8531833
• 负责人: Joseph J Eron
• 金额: $ 33.05万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8531833
• 关键词: AIDS Malignancy Consortium; AIDS clinical trial group; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Acute; Advocate; Applications Grants; Area; Behavioral; Behavioral Research; Blood; Cancer Center; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Clinical Research; Collaborations; Communities; Complex; County; Coupled; Criminal Justice; Data; Databases; Development; Discipline; Drug Formulations; Early Intervention; Epidemiologist; Epidemiology; Evaluation; Face; Faculty; Feedback; Fostering; Genotype; Goals; Grant; Growth; HIV; HIV Infections; Health; Health Services Research; Housing; Human Resources; Individual; Industry; Institutional Review Boards; Instruction; International; Joints; K-Series Research Career Programs; Laboratories; Lead; Leadership; Link; Malignant Neoplasms; Manuscripts; Mentors; Mentorship; Methods; Molecular; North Carolina; Pathogenesis; Patients; Population; Populations at Risk; Postdoctoral Fellow; Prema; Prevention; Research; Research Design; Research Personnel; Research Priority; Research Project Grants; Research Support; Resources; Risk; Role; Sampling; Scientist; Services; Specimen; Strategic Planning; Students; Surveys; Testing; Tissues; Training; Translational Research; United States National Institutes of Health; Work; base; biobank; cohort; design; epidemiological model; experience; graduate student; improved; innovation; meetings; neoplasm registry; patient oriented; population based; programs; repository; research study; screening; skills; success; translational study; transmission process; willingness; AIDS Malignancy Consortium; AIDS clinical trial group; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Acute; Advocate; Applications Grants; Area; Behavioral; Behavioral Research; Blood; Cancer Center; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Clinical; Clinical Research; Collaborations; Communities; Complex; County; Coupled; Criminal Justice; Data; Databases; Development; Discipline; Drug Formulations; Early Intervention; Epidemiologist; Epidemiology; Evaluation; Face; Faculty; Feedback; Fostering; Genotype; Goals; Grant; Growth; HIV; HIV Infections; Health; Health Services Research; Housing; Human Resources; Individual; Industry; Institutional Review Boards; Instruction; International; Joints; K-Series Research Career Programs; Laboratories; Lead; Leadership; Link; Malignant Neoplasms; Manuscripts; Mentors; Mentorship; Methods; Molecular; North Carolina; Pathogenesis; Patients; Population; Populations at Risk; Postdoctoral Fellow; Prema; Prevention; Research; Research Design; Research Personnel; Research Priority; Research Project Grants; Research Support; Resources; Risk; Role; Sampling; Scientist; Services; Specimen; Strategic Planning; Students; Surveys; Testing; Tissues; Training; Translational Research; United States National Institutes of Health; Work; base; biobank; cohort; design; epidemiological model; experience; graduate student; improved; innovation; meetings; neoplasm registry; patient oriented; population based; programs; repository; research study; screening; skills; success; translational study; transmission process; willingness

PROJECT SUMMARY (See instructions): The Clinical Core of the FHI/RTI/UNC CFAR is led by Dr. Joseph Eron, Director, Dr. Prema Menezes, co-Director, and Dr. Sonia Napravnik, Core Epidemiologist, who also leads the UNC CFAR HIV Clinical Cohort (UCHCC). The goals of the Clinical Core are 1) to enhance the clinical, translational and epidemiological research capacity of a diverse array CFAR investigators by providing essential services such as subject recruitment, sample access and regulatory assistance, study design and management, study coordinator services and unique resources such as access to a detailed clinical cohort with links to larger cohorts and specimen and tissue repositories coupled with state-of-the-art epidemiological expertise and 2) to provide leadership and foster collaboration in high priority research areas and provide mentorship to students and faculty and educational opportunities to the wider community. The Core includes a dedicated staff of over 15 individuals with the needed skills to accomplish these goals. The Core is housed centrally on the UNC Health Affairs campus and is easily accessible to investigators either because of close proximity or because the leadership and several of our services are readily available electronically facilitating interactions with FHl, RTI and international investigators. The Core supports research from molecular to geographic (even combining the extremes) using methods ranging from patient oriented qualitative work to complex epidemiological modeling. Over the past four years the Core served over 100 investigators on over 150 projects supported by the NIH, the Agency for Health Care Research and Quality (AHRQ) and CDC among others. The Core supports multiple CFARiCFAR research projects and NIH-sponsored HIV networks while having a strong mentoring presence. The Core also provides data, leadership and investigator access to two large HIV-focused collaborative cohorts. The Clinical Core is essential for the continued success of the UNC/FHI/RTI CFAR as the services and research opportunities provided by the Core and the UCHCC have proved invaluable to investigators and are not duplicated by other Cores or facilities on the UNC, FHl or RTI campuses.

项目摘要（请参阅说明）： FHI/RTI/UNC CFAR的临床核心由Joseph Eron博士，主任Prema Menezes博士，联合导演Prema Menezes博士和核心流行病学家Sonia Napravnik博士领导，后者还领导UNC CFAR HIV HIV Clinical Clinical Colort（UCHCC）。临床核心的目标是1）通过提供主题招聘，样本访问和监管援助，研究设计和管理等基本服务，以增强各种阵列CFAR研究人员的临床，转化和流行病学研究能力，研究 协调员服务和独特的资源，例如访问详细的临床队列，并与更大的队列，标本和组织存储库相连，再加上最先进的流行病学专业知识，以及2），以提供高优先级研究领域的领导和促进协作，并向学生，教职员工和教育机会提供给更大社区的指导机会。核心包括一个专用的 超过15个人拥有实现这些目标所需技能的员工。该核心位于UNC健康事务校园中心，由于近距离接近，调查人员很容易接触，或者由于我们的领导能力和我们的一些服务很容易以电子方式促进与FHL，RTI和国际调查人员的互动。 核心支持从分子到地理（甚至结合极端）的研究，使用从患者面向定性工作到复杂的流行病学建模的方法。在过去的四年中 护理研究与质量（AHRQ）和CDC等。核心支持多个Cfaricfar研究项目和NIH赞助的HIV网络，同时拥有强大的指导影响力。该核心还提供数据，领导力和调查员访问两个以HIV为重点的大型合作群体。 临床核心对于UNC/FHI/RTI CFAR的持续成功至关重要，因为核心和UCHCC提供的服务和研究机会对研究人员证明是非常宝贵的，并且并未被UNC，FHL或RTI校园的其他内核或设施重复。