Comprehensive analysis of inflammatory bowel disease using by genome-wid genetic and epigenetic association studies

通过全基因组遗传和表观遗传关联研究对炎症性肠病进行综合分析

• 批准号: 26293180
• 负责人: YAMAZAKI Keiko
• 金额: $ 10.65万
• 依托单位: Nihon University (2016-2017)Institute of Physical and Chemical Research (2014-2015)
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2014
• 资助国家: 日本
• 起止时间: 2014-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26293180/
• 关键词: 炎症性腸疾患; 全ゲノム関連解析; 薬剤応答性; エピゲノム解析; 薬剤反応性

项目成果

University Medical Centre Groningen(オランダ)

格罗宁根大学医学中心（荷兰）

A cross-ethnic survey of CFB and SLC44A4, Indian ulcerative colitis GWAS hits, underscores their potential role in disease susceptibility

印度溃疡性结肠炎 GWAS 命中的 CFB 和 SLC44A4 的跨种族调查强调了它们在疾病易感性中的潜在作用

• DOI: 10.1038/ejhg.2016.131
• 发表时间: 2016
• 影响因子: 5.2
• 作者: Gupta Aditi;Juyal Garima;Sood Ajit;Midha V;ana;Yamazaki Keiko;Vich Vila Arnau;Esaki Motohiro;Matsui Toshiyuki;Takahashi Atsushi;Kubo Michiaki;Weersma Rinse K;Thelma B K
• 通讯作者: Thelma B K

Disease susceptibility genes shared by primary biliary cirrhosis and Crohn’s disease in the Japanese population

日本人群中原发性胆汁性肝硬化和克罗恩病共有的疾病易感基因

• DOI: 10.1038/jhg.2015.59
• 发表时间: 2015
• 影响因子: 3.5
• 作者: Yoshihiro Aiba; Keiko Yamazaki; Nao Nishida; Minae Kawashima; Yuki Hitomi; Hitomi Nakamura; Atsumasa Komori; Yuta Fuyuno; Atsushi Takahashi; Takaaki Kawaguchi; Masakazu Takazoe; Yasuo Suzuki; Satoshi Motoya Toshiyuki Matsui Motohiro Esaki; Takayuki Matsum
• 通讯作者: Takayuki Matsum

A genome-wide association study by using imputed genotypes identifies a susceptibility locus for Crohn's disease in a Japanese population

一项使用估算基因型的全基因组关联研究确定了日本人群中克罗恩病的易感位点

• 发表时间: 2014
• 作者: Yamazaki K; Umeno J; Takahashi A; Hirano A; Johnson T; Morizono T; Kawaguchi T; Takazoe M; Yamada T; Suzuki Y; Tanaka H; Motoya S; Hosokawa M; Arimura Y; Shinomura Y; Matsui T; Matsumoto T; Iida M; Tsunoda T; Nakamura Y; Kamatani N; Kubo M
• 通讯作者: Kubo M

University of Delhi South Campus/Deyanand Medical College and Hospital(インド)

德里大学南校区/德亚南德医学院和医院（印度）