Clarification of local GnRH-induced luteolysis in the rat ovaryand challenge to control thecorpus luteumlife span
大鼠卵巢局部 GnRH 诱导的黄体溶解的澄清和控制黄体寿命的挑战
基本信息
- 批准号:22780263
- 负责人:
- 金额:$ 2.58万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Young Scientists (B)
- 财政年份:2010
- 资助国家:日本
- 起止时间:2010 至 2011
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Thecorpusluteum regresses rapidlyif prolactin is not adequately supplied until the afternoon on diestrus 2.In this study, we focused onthemechanisms of time-specific determinationof thecorpus luteum life span in rats. Eventually, we clarified that1) local gonadotropin-releasing hormone could alter the expression ratio of prolactin receptor isoforms in corpus luteum, and 2) we could control theduration of luteal phase by changing that expression ratioartificially.
如果直到第二发情间期下午催乳素供应不足,黄体就会迅速退化。在这项研究中,我们重点研究了大鼠黄体寿命的时间特异性测定机制。最终,我们阐明:1)局部促性腺激素释放激素可以改变黄体中催乳素受体亚型的表达比例,2)我们可以通过人为改变该表达比例来控制黄体期的持续时间。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Effects of estrogen on growth hormone pulsatility in peripheral blood and neuropeptide profiles in the cerebrospinal fluid of goats
雌激素对山羊外周血生长激素脉动和脑脊液神经肽谱的影响
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:1.8
- 作者:Yonezawa T; Mogi K; Li JY; Sako R; Manabe N; Yamanouchi K; Nishihara M
- 通讯作者:Nishihara M
Anti-ovulatory effects of RU486 and trilostane involve impaired cyclooxygenase-2 expression and mitoticactivity of follicular granulosa cells in rats
RU486 和曲洛斯坦的抗排卵作用涉及大鼠卵泡颗粒细胞的环氧合酶 2 表达和有丝分裂活性受损
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:0
- 作者:Mori D; Ogino N; Yonezawa T; Kawaminami M; Kurusu S
- 通讯作者:Kurusu S
Molecular cloning and expression of canine prolactin gene
犬催乳素基因的分子克隆及表达
- DOI:
- 发表时间:2010
- 期刊:
- 影响因子:0
- 作者:Hashimoto O; Yonezawa T; Sugiyama Y; Kawaminami M; Hasegawa Y
- 通讯作者:Hasegawa Y
Changes in number of ovarian mast sells during estrous cycle, pseudopregnancy and pregnancy of rats : implications for the expression of gonadotropin releasinghormone(GnRH) in the ovary
大鼠动情周期、假孕和妊娠期间卵巢肥大数量的变化:对卵巢促性腺激素释放激素(GnRH)表达的影响
- DOI:
- 发表时间:2011
- 期刊:
- 影响因子:0
- 作者:ラウハラッチャダタニン・ティタリー;寺島涼太;米澤智洋;久留主志朗;汾陽光盛
- 通讯作者:汾陽光盛
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YONEZAWA Tomohiro其他文献
Rapid visualization of mammary gland tumor lesions of dogs using the enzyme-activated fluorogenic probe; γ-glutamyl hydroxymethyl rhodamine green
使用酶激活荧光探针快速可视化狗的乳腺肿瘤病变;
- DOI:
10.1292/jvms.22-0003 - 发表时间:
2022 - 期刊:
- 影响因子:1.2
- 作者:
HIROSE Yui;UCHIDA Mona;TSUBOI Masaya;NAKAGAWA Takayuki;YAGA Leo;MAEDA Shingo;MOMOI Yasuyuki;KURIKI Yugo;KAMIYA Mako;URANO Yasuteru;YONEZAWA Tomohiro - 通讯作者:
YONEZAWA Tomohiro
Clinical assessment of testosterone analogues for urethral sphincter mechanism incompetence in ten spayed female dogs
睾酮类似物治疗十只绝育母犬尿道括约肌机制不全的临床评估
- DOI:
10.1292/jvms.20-0515 - 发表时间:
2021 - 期刊:
- 影响因子:1.2
- 作者:
NISHI Reo;MOTEGI Tomoki;MAEDA Shingo;TAMAHARA Satoshi;MOMOI Yasuyuki;MATSUKI Naoaki;YONEZAWA Tomohiro - 通讯作者:
YONEZAWA Tomohiro
Multiple acquired portosystemic shunts secondary to primary hypoplasia of the portal vein in a cat
猫继发于门静脉原发性发育不全的多发性门体分流
- DOI:
10.1292/jvms.17-0648 - 发表时间:
2018 - 期刊:
- 影响因子:1.2
- 作者:
SUGIMOTO Satoko;MAEDA Shingo;TSUBOI Masaya;SAEKI Kohei;CHAMBERS James K.;YONEZAWA Tomohiro;FUKUSHIMA Kenjiro;FUJIWARA Reina;UCHIDA Kazuyuki;TSUJIMOTO Hajime;MATSUKI Naoaki;OHNO Koichi - 通讯作者:
OHNO Koichi
Rapid visualization of mammary gland tumor lesions of dogs using the enzyme-activated fluorogenic probe; γ-glutamyl hydroxymethyl rhodamine green
使用酶激活荧光探针快速可视化狗的乳腺肿瘤病变;
- DOI:
10.1292/jvms.22-0003 - 发表时间:
2022 - 期刊:
- 影响因子:1.2
- 作者:
HIROSE Yui;UCHIDA Mona;TSUBOI Masaya;NAKAGAWA Takayuki;YAGA Leo;MAEDA Shingo;MOMOI Yasuyuki;KURIKI Yugo;KAMIYA Mako;URANO Yasuteru;YONEZAWA Tomohiro - 通讯作者:
YONEZAWA Tomohiro
Rapid visualization of mammary gland tumor lesions of dogs using the enzyme-activated fluorogenic probe; γ-glutamyl hydroxymethyl rhodamine green
使用酶激活荧光探针快速可视化狗的乳腺肿瘤病变;
- DOI:
10.1292/jvms.22-0003 - 发表时间:
2022 - 期刊:
- 影响因子:1.2
- 作者:
HIROSE Yui;UCHIDA Mona;TSUBOI Masaya;NAKAGAWA Takayuki;YAGA Leo;MAEDA Shingo;MOMOI Yasuyuki;KURIKI Yugo;KAMIYA Mako;URANO Yasuteru;YONEZAWA Tomohiro - 通讯作者:
YONEZAWA Tomohiro
YONEZAWA Tomohiro的其他文献
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{{ truncateString('YONEZAWA Tomohiro', 18)}}的其他基金
Regulation of the corpus luteum-life span via alternative splicing of prolactin receptors
通过催乳素受体的选择性剪接调节黄体寿命
- 批准号:
24380161 - 财政年份:2012
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Mechanisms of luteolysis via local GnRH as a follicular developing signal.
通过局部 GnRH 作为卵泡发育信号的黄体溶解机制。
- 批准号:
20780210 - 财政年份:2008
- 资助金额:
$ 2.58万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
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22K06033 - 财政年份:2022
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Study on the role of annexin A1 in the regulation of gonadotropin secretion from the pituitary gland
膜联蛋白A1对垂体促性腺激素分泌调节作用的研究
- 批准号:
21K05964 - 财政年份:2021
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Anxa5 在中枢和周围神经系统中的功能作用以及 AAV 给药在基因治疗中的应用
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