Comprehensive Assessment for improvement of QOL and effectiveness brought by AMD treatment.

综合评估AMD治疗带来的生活质量改善和效果。

• 批准号: 22791655
• 负责人: TAMURA Hiroshi
• 金额: $ 2.58万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791655/
• 关键词: 加齢黄斑変性; QOL; 脈絡膜新生血管; 新生血管; 強度近視; 近視性脈絡膜新生血管; 中心性漿液性網脈絡膜症

New findings of age-related macular degeneration or its relative disease such as central serous chorioretinopathy and choroidal neovascularization secondary to angioid streaks are found to understand the pathophysiologies of these desease. Experiences in comparative effectiveness research for cataract surgery were successfully applied to age-related macular degeneration treatment. New findings of effectiveness in treatment for AMD were also revealed from the relationship between second eye involvement of AMD and ARMS2 genotype.

年龄相关性黄斑变性或其相关疾病（例如中心性浆液性脉络膜视网膜病变和继发于血管样条纹的脉络膜新生血管）的新发现有助于了解这些疾病的病理生理学。白内障手术比较效果研究的经验成功应用于年龄相关性黄斑变性的治疗。 AMD 的第二只眼受累与 ARMS2 基因型之间的关系也揭示了 AMD 治疗有效性的新发现。

项目成果

Idiopathic macular telangiectasia ; microperimetry, retinal structure ; photoreceptor inner and outer segment junction line ; optical coherence tomo graphy

特发性黄斑毛细血管扩张症;

• 发表时间: 2012
• 作者: Takayama K; Ooto S; Tamura H; et a.l
• 通讯作者: et a.l

Factors Associated with the Response of Age-related Macular Degeneration to Intravitreal Ranibizumab Treatment

与年龄相关性黄斑变性对玻璃体内雷珠单抗治疗反应相关的因素

• DOI: 10.1016/j.ajo.2012.01.010
• 发表时间: 2012
• 影响因子: 4.2
• 作者: Yamashiro K; Tomita K; Tsujikawa A; Nakata I; Akagi
• 通讯作者: Akagi

Prognostic factors for visual outcomes 2-years after intravitreal bevacizumab for myopic choroidal neovascularization.

玻璃体内注射贝伐单抗治疗近视脉络膜新生血管后 2 年视力结果的预后因素。

• 发表时间: 2011
• 影响因子: 3.9
• 作者: Nakanishi H; Tsujikawa A; Yodoi Y; Ojima Y; Otani A; Tamura H; et al.
• 通讯作者: et al.

Development of polypoidal lesions in age-related macular degeneration

年龄相关性黄斑变性息肉状病变的发展

• DOI: 10.1038/eye.2010.232
• 发表时间: 2011
• 作者: Tsujikawa A; Ojima Y; Yamashiro K; Ooto S; Tamura H; Nakata I; Yoshimura N.
• 通讯作者: Yoshimura N.

Treatment of Polypoidal Choroidal Vasculopathy with Intravitreal Injection of Bevacizumab

玻璃体内注射贝伐珠单抗治疗息肉状脉络膜血管病

• 发表时间: 2010
• 影响因子: 2.4
• 作者: Tsujikawa A; Ooto S; Yamashiro K; Tamura H; et al.
• 通讯作者: et al.