Investigation of Pathophysiology and Innovative Treatment for Macular Degeneration with Thermosensitive Liposome

热敏脂质体黄斑变性的病理生理学研究和创新治疗

• 批准号: 20791249
• 负责人: TAMURA Hiroshi
• 金额: $ 2.75万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20791249/
• 关键词: 黄斑変性; リボソーム; 脈絡膜新生血管; ポリープ状脈絡膜血管症; 強度近視; 近視性脈絡膜新生血管

New findings of age-related macular degeneration or its relative disease such as central serous chorioretinopathy and choroidal neovascularization secondary to angioid streaks are found to understand the pathophysiologies of these desease. For more improvement in treatment for age-related macular degeneration, problems and comparative merits among the current treatments are also revealed. These accomplishments would be helpful for development of innovative treatment for age-related macular degeneration.

年龄相关性黄斑变性或其相关疾病（例如中心性浆液性脉络膜视网膜病变和继发于血管样条纹的脉络膜新生血管）的新发现有助于了解这些疾病的病理生理学。为了进一步改善年龄相关性黄斑变性的治疗，还揭示了当前治疗方法中的问题和比较优点。这些成就将有助于开发年龄相关性黄斑变性的创新治疗方法。

项目成果

Photodynamic Therapy Combined with Low-dose Intravitreal Triamcinolone Acetonide for Age-related Macular Degeneration Refractory to Photodynamic Therapy Alone

光动力疗法联合低剂量玻璃体内注射曲安奈德治疗单独光动力疗法难治的年龄相关性黄斑变性

• 发表时间: 2008
• 作者: Iwama D; Otani A; Sasahara M; Yodoi Y; Gotoh N; Tamura H; et.al
• 通讯作者: et.al

estoration of outer segments of foveal photoreceptors after resolution of central serous chorioretinopathy.

中心性浆液性脉络膜视网膜病变消退后中心凹感光器外段的恢复。

• 发表时间: 2010
• 作者: Ojima Y; Tsujikawa A; Yamashiro K; Ooto S; Tamura H; Yoshimura N.
• 通讯作者: Yoshimura N.

Thickness of photoreceptor layers in polypoidal choroida vasculopathy and central serous chorioretinopathy.

息肉状脉络膜血管病变和中心性浆液性脉络膜视网膜病变中感光层的厚度。

• 发表时间: 2010
• 作者: Ooto S; Tsujikawa A; Mori S; Tamura H; Yamashiro K; Yoshimura N.
• 通讯作者: Yoshimura N.

Punctate Hyperfluorescent Spots Associated with Central Serous Chorioretinopathy as Seen on Indocyanine Green Angiography.

吲哚菁绿血管造影显示与中心性浆液性脉络膜视网膜病变相关的点状高荧光斑点。

• 发表时间: 2010
• 作者: Tsujikawa A; Ojima Y; Yamashiro K; Ooto S; Tamura H; et al.
• 通讯作者: et al.

Central Retinal Sensitivity After Intravitreal Injection of Bevacizumab for Myopic Choroidal Neovascularization.

玻璃体内注射贝伐单抗治疗近视脉络膜新生血管后的中央视网膜敏感性。

• 发表时间: 2009
• 作者: Yodoi Y; Tsujikawa A; Nakanishi H; Otani A; Tamura H; Ojima Y; Hayashi H; Yoshimura N.
• 通讯作者: Yoshimura N.