Light environment suitable for our daily activities

适合我们日常活动的光环境

• 批准号: 20770200
• 负责人: TAKASU Nana
• 金额: $ 2.91万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20770200/
• 关键词: 光環境; 生体リズム; 睡眠; 睡眠覚醒; メラトニン; 深部体温

Circadian rhythms observed in all psychophysiological functions are produced by the circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Intrinsically, the SCN oscillates with slightly longer than 24 hr, but generally, repeated bright light exposures at 24-hr intervals entrain the endogenous period. However, recently, irregular sleep-wake habits have been established among young people, which have disrupted the light-dark cycle. Furthermore, the number of people who are suffering from psychophysiological disorder is increasing. Therefore, we aimed at clarifying relations between the habitual sleep-wake habits and daytime psychophysiological states. In results, we demonstrated that daytime psychophysiological functions were deteriorated when the irregularity of sleep-wake rhythm was exceeded more than 3-4 hours. However, the deteriorated psychophysiological functions were recovered when irregular sleep-wake rhythm was regularized for 6 days. The present findings suggested that the regularization of sleep-wake schedule could modulate the daytime psychophysiological functions in such a way as is more adaptive to the daytime activity.

所有心理生理​​功能中观察到的昼夜节律都是由位于下丘脑视交叉上核（SCN）的生物钟产生的。本质上，SCN 的振荡时间略长于 24 小时，但一般来说，以 24 小时为间隔重复进行强光照射会夹带内源性周期。然而，近年来，年轻人养成了不规则的睡眠-觉醒习惯，扰乱了明暗循环。此外，患有心理生理​​障碍的人数正在增加。因此，我们的目的是阐明习惯性睡眠-觉醒习惯与白天心理生理状态之间的关系。结果表明，当睡眠-觉醒节律不规则超过 3-4 小时以上时，日间心理生理功能就会恶化。然而，当不规律的睡眠-觉醒节律规律化6天后，恶化的心理生理功能得到恢复。目前的研究结果表明，睡眠-觉醒时间表的规律化可以以更适应白天活动的方式调节白天的心理生理功能。