The development of a pain treatment device using sonification technology

利用超声波技术开发疼痛治疗装置

• 批准号: 23659743
• 负责人: NAKAE Aya
• 金额: $ 2.5万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23659743/
• 关键词: 情動; 痛み; sonification; 音; 実験的痛み; 国際情報交換; 可聴化技術; 国際情報交流（ドイツ）

We conducted the research focused on “pain and sound” and performed the basic data to reflect the painful situation to create a device that can grasp the pain in the "sound". Firstly we tried to use many kinds of monitoring systems and we found out that “Perfusion Index", which can be analyzed using pulse oximeter and reflect the autonomic response analyzed by peripheral perfusion change, was the most sensitive indicator . Then, we performed the experimental heat pain study with comfortable and unpleasant sounds, and analyzed the subjective pain intensity and perfusion index. It was revealed that perfusion index was a more sensitive indicator for younger peoplethan for older people. Moreover, uncomfortable sound effect was almost the same, but the sound effect which we predicted it comfortable for everybody has an individual differences. The average subjective pain intensity was higher in patients with chronic pain compared to healthy subjects. Patients with chronic pain tended not to be influenced their pain intensity by any sounds

我们进行了专注于“疼痛和声音”的研究，并执行了基本数据，以反映痛苦的情况，以创建一种可以抓住“声音”中痛苦的设备。首先，我们试图使用多种监测系统，发现“灌注指数”，可以使用脉搏氧对其进行分析，并反映出通过周围灌注变化分析的自主响应是最敏感的指标。然后，我们以舒适和不愉快的声音进行了实验性热痛研究，并分析了受试者的疼痛强度和灌注指数。据透露，灌注指数对年轻人对老年人来说是更敏感的指标。此外，不舒服的声音效果几乎是相同的，但是我们预测它对每个人都具有个体差异的声音效果。与健康受试者相比，慢性疼痛患者的平均主观疼痛强度更高。慢性疼痛的患者往往不会受到任何声音影响其疼痛强度的

项目成果

実験的痛みと末梢循環の変化

实验性疼痛和外周循环的变化

• 发表时间: 2012
• 作者: 西村俊樹;中江文;柴田政彦;眞下節
• 通讯作者: 眞下節

Mechanisms of pain

• DOI: 10.1073/pnas.211373398
• 发表时间: 2001-10-09
• 期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
• 影响因子: 11.1
• 作者: Stucky, CL;Gold, MS;Zhang, X
• 通讯作者: Zhang, X

Pain modulation by negative and positive emotional sounds

通过消极和积极的情绪声音调节疼痛

• 发表时间: 2013
• 期刊: Proceedings of 4^<th> International Congress of Neuropathic pain
• 作者: Aya Nakae;Thomas Hermann;Takashi Ikeda;Teruko Sakurai;Tomonori Adachi;Hiroshi Ito;Toshiki Nishimura;Masahiko Shibata;Mariko Osaka;Takashi Mashimo
• 通讯作者: Takashi Mashimo