Experimental study of the effectiveness of CO2 for the brain protection after cardiopulmonary arrest

CO2对心肺骤停后脑保护作用的实验研究

• 批准号: 22592008
• 负责人: OSHIMA Kiyohiro
• 金额: $ 2.91万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592008/
• 关键词: 心肺停止; 心肺蘇生; 脳保護; 二酸化炭素; 虚血再灌流傷害; 自己心拍再開; アニオンギャップ; アルブミン補正アニオンギャップ; 温阻血; ATP感受性Kチャンネル

WE reported the effectiveness of the introduction of percutaneous cardiopulmonary support system (PCPS) and hemodialysis in patients with cardiopulmonary arrest (CPA) due to accidental hypothermia. We aiso reported that anion gap (AG) and albumin-corrected AG (ACAG) were useful predictors of return of spontaneous circulation (ROSC) in patients with CPA. In addition, we evaluated the usefulness of fibrin degradation products (FDP) and D-dimer levels in blood to predict ROSC in patients with CPA compared with AG and ACAG.

我们报道了由于意外体温过低而引入经皮心肺支持系统（PCP）和血液透析的有效性。我们的AISO报道说，CPA患者的自发循环恢复（ROSC）的回报指标，阴离子间隙（Ag）和白蛋白校正的AG（ACAG）是有用的预测指标。此外，我们评估了与AG和ACAG相比，我们评估了血液中纤维蛋白降解产物（FDP）和D-二聚体水平的有用性，以预测CPA患者的ROSC。

项目成果

Usefulness of fibrin degradation products and d-dimer levels as biomarkers that reflect the severity of trauma

• DOI: 10.1097/ta.0b013e31828cc967
• 发表时间: 2013-05-01
• 期刊: JOURNAL OF TRAUMA AND ACUTE CARE SURGERY
• 影响因子: 3.4
• 作者: Hagiwara, Shuichi;Oshima, Kiyohiro;Tamura, Jun'ichi
• 通讯作者: Tamura, Jun'ichi

The influence of the ECG pattern in patients treated with ECPR (SOS-KANTO 2012 study interim report)

心电图模式对 ECPR 治疗患者的影响（SOS-KANTO 2012 年研究中期报告）

• 发表时间: 2014
• 作者: Kaneko K;Hagiwara S;Oshima K;Ogasawara T;Tahara Y;Nagao K;Yaguchi A;Morimura N
• 通讯作者: Morimura N

補助循環を用いた心肺蘇生

辅助循环心肺复苏

• 发表时间: 2011
• 作者: 萩原周一;金子稔;青木誠;村田将人;神戸将彦;古川和美;中村卓郎;大山良雄;田村遵一;大嶋清宏;大嶋清宏
• 通讯作者: 大嶋清宏

Survival after 385 min of cardiopulmonary resuscitation with extracorporeal membrane oxygenation and rewarming with haemodialysis for hypothermic cardiac arrest

• DOI: 10.1016/j.resuscitation.2010.11.032
• 发表时间: 2011-06-01
• 期刊: RESUSCITATION
• 影响因子: 6.5
• 作者: Hagiwara, Shuichi;Yamada, Takuro;Oshima, Kiyohiro
• 通讯作者: Oshima, Kiyohiro

Septic shock caused by Klebsiella oxytoca: An autopsy case and a survival case with driving Extracorporeal Membrane Oxygenation

产酸克雷伯菌引起感染性休克：一例尸检病例及一例驱动体外膜氧合的生存病例

• 发表时间: 2013
• 期刊: Hippokratia
• 影响因子: 0.6
• 作者: Hagiwara S;Murata M;Aoki M;Kaneko M;Oshima K.
• 通讯作者: Oshima K.