Experimental research of immunological tolerance in allograft from cadaveric donors for clinical trial
尸体供体同种异体移植物免疫耐受临床试验研究
基本信息
- 批准号:22390246
- 负责人:
- 金额:$ 11.98万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:2010
- 资助国家:日本
- 起止时间:2010 至 2012
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
During the study period, it was revealed in Rhesus monkeys that anti-human thymocyte globulin may reduce the number of T-cell, that chimerism of peripheral blood mononuclear cells (PMBC) can be detected and that bone marrow transplant can be done by perfusion technique. Although chimerism of PBMC was not observed, mixed lymphocyte reaction (MLR) against the donor lymphocytes was significantly reduced compared to that against lymphocytes of third party monkey
研究期间,在恒河猴中发现抗人胸腺细胞球蛋白可以减少T细胞数量,可以检测到外周血单核细胞(PMBC)嵌合,并可以通过灌注技术进行骨髓移植。虽然没有观察到PBMC的嵌合现象,但与第三方猴淋巴细胞相比,针对供体淋巴细胞的混合淋巴细胞反应(MLR)显着减少
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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FUKUSHIMA Norihide其他文献
FUKUSHIMA Norihide的其他文献
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{{ truncateString('FUKUSHIMA Norihide', 18)}}的其他基金
Identification and therapeuticeffect of growth factor inducingmyoblast sheet transplantation in infarcted rat hearts
生长因子诱导成肌细胞片移植对梗死大鼠心脏的鉴定及治疗作用
- 批准号:
18390376 - 财政年份:2006
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
ESTABLISHMENT OF MULTIORGAN PROCUREMENT SYSTEM FROM NO-HEART-BEATING DONOR USING PERCUTANEOUS CARDIOPULMONARY BYPASS
经皮心肺转流术无心跳供体多器官获取系统的建立
- 批准号:
16390396 - 财政年份:2004
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
ESTABLISHMENT OF IMMUNOSUPPRRESIVE METHOD FOR CLINICAL DISCORDANT XENOGENEIC CARDIAC TRANSPLANTATION
临床不一致异种心脏移植免疫抑制方法的建立
- 批准号:
14370412 - 财政年份:2002
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
ESTABLISHMENT OF NEW IMMUNOSUPPRESSIVE STRATEGY USING GENE TRANSFECTION TECHNIQUE
利用基因转染技术建立新的免疫抑制策略
- 批准号:
12470274 - 财政年份:2000
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
ESTABLISHMENT OF MULTIORGAN PROCUREMENT SYSTEM FROM NO-HEART-BEATING DONOR USING PERCUTANEOUS CARDIOPULMONARY BYPASS
经皮心肺转流术无心跳供体多器官获取系统的建立
- 批准号:
10671254 - 财政年份:1998
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
ESTABLISHMENT OF NEW IMMUNOSUPPRESSIVE STRATEGY USING GENE TRANSFECTION TECHNIQUE
利用基因转染技术建立新的免疫抑制策略
- 批准号:
10557124 - 财政年份:1998
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Prevention of hypoxic brain damage by in vivo transfection through the carotid artery in cirsulatory arrest
通过颈动脉体内转染预防循环骤停中的缺氧性脑损伤
- 批准号:
08671526 - 财政年份:1996
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
ESTABLISHMENT OF IMMUNOSUPPRRESIVE METHOD FOR CLINICAL DISCORDANT XENOGENEIC CARDIAC TRANSPLANTATION
临床不一致异种心脏移植免疫抑制方法的建立
- 批准号:
07457292 - 财政年份:1995
- 资助金额:
$ 11.98万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
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