Investigation on the methods that will overcome crossing-fiber problem of diffusion tensor tractography.

研究克服扩散张量纤维束成像的交叉纤维问题的方法。

• 批准号: 19591429
• 负责人: YAMADA Kei
• 金额: $ 2.75万
• 依托单位: Kyoto Prefectural University of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19591429/
• 关键词: 交差線維; 神経機能; magnetic resonance imaging; 拡散強調画像; 拡散異方性; fiber tracking; tractography; fractional anisotropy

The purpose of this investigation was to conduct a research on methods that will overcome the crossing-fiber problem on diffusion-tensor tractography. More specifically, we tested the feasibility of using high angular resolution diffusion imaging (HARDI)-based multi-tensor tractography to depict motor pathways. We tested this on patients with brain tumors. Ten patients were scanned using a 1.5T clinical MR unit. Data postprocessing was performed using both the conventional single- and multi-tensor methods. Motor fibers on both lesional and contralesional sides were successfully depicted by both the single-tensor and multi-tensor techniques. However, with the single-tensor model, the depiction of motor pathways was typically limited to the fibers of trunk areas. We also assessed the value of using high b-factor. This investigation indicated that the b factor between 1000 and 3000 will have less effect on the depiction of crossing fibers.

这项研究的目的是对可以克服扩散式拖拉术的交叉纤维问题进行研究。更具体地说，我们测试了使用高角度分辨率扩散成像（HARDI）的多张式拖拉机来描绘电动途径的可行性。我们对脑肿瘤患者进行了测试。使用1.5T临床MR单位对十名患者进行扫描。使用常规的单张和多觉方法进行数据后处理。单张纸和多张量技术都成功地描绘了病变侧和对侧侧面的运动纤维。但是，使用单张镜模型，电动途径的描述通常仅限于躯干区域的纤维。我们还评估了使用高B因子的价值。这项研究表明，1000至3000之间的B因子对穿越纤维的描述的影响较小。

项目成果

Multi-tensor tractography enables better depiction of motor pathways 15th annual meeting of International Society of Magnetic Resonance in Medicine

多张量纤维束成像可以更好地描述运动路径国际医学磁共振学会第 15 届年会

• 发表时间: 2007
• 作者: Yamada K;Sakai K;Hoogenraad FG;Holthuizen R;Akazawa K;Ito H;Oouchi H;Matsushima S;Kubota T;Nishimura T
• 通讯作者: Nishimura T

Diagnostic imaging ; In : Bernstein M ed. Neuro-Oncology : The Essentials 2nd edition ; 56-77

诊断成像；

• 发表时间: 2008
• 作者: Yamada K;Sorensen AG.
• 通讯作者: Sorensen AG.

Crossing fiber problemを解決するのに高いb値は必要か?.

解决纤维交叉问题是否需要高b值？

• 发表时间: 2008
• 作者: 赤澤健太郎;山田惠;後藤眞理子;松島成典;西村恒彦
• 通讯作者: 西村恒彦

Clinical MR tractography; past, present, and future.

临床磁共振纤维束成像；

• 发表时间: 2009
• 期刊: Medical Mundi 53
• 作者: Yamada K;Akazawa K;Yuen S;Nishimura T
• 通讯作者: Nishimura T

Morning categorical course Stroke: "A Brain Attack

上午分类课程中风：“大脑攻击

• 发表时间: 2008
• 作者: Yamada K;Akazawa K;Yuen S;Goto M;Matsushima S;Takahata A;Nishimura T;Kei Yamada;Kei Yamada
• 通讯作者: Kei Yamada