Development of one-dimensional sharing detectors and application to imaging system

一维共享探测器的研制及其在成像系统中的应用

基本信息

批准号：
15390365
负责人：
YAMAMOTO Seiichi
金额：
$ 9.22万
依托单位：
Kobe City College of Technolog
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

项目摘要

We propose and test a 1-dimentional sharing block detector using dual photo-multiplier tubes (PMT). The detector consists of scintillator blocks and dual PMTs. The dual PMTs are optically coupled on the scintillator blocks and overlap in one dimensional. With this configuration, the scintillator size of the block detector can be reduced to half that of a conventional block detector in one direction, and isotropic spatial resolution can be obtained in transaxial and axial directions using commercially available dual PMTs. First, we measure the position and energy response for minimum configuration ; one GSO block and two dual PMTs. The size of a single GSO is 2.9 mm×2.9 mm×20 mm. The scintillators are arranged in an 8×8 matrix with multi-layer optical film inserted partly between scintillators to obtain the resolved position response. We obtain good position and energy responses with this configuration. Next, we fabricate a 1-D sharing block detector with five GSO blocks and six dual PM … More Ts. With this configuration, we also obtain reasonable position and energy responses. These results indicate that the proposed 1-D sharing block detector is a promising solution for developing high-resolution and low cost PET systems.Also we developed a large field of view (FOV) coincidence imaging system using the one-dimensional sharing detector. The imaging system consists of four sets of one-dimensional sharing block detectors and a single gamma probe and measures coincidence between these two detectors. The one-dimensional sharing detector uses 5 GSO blocks optically coupled to 6 dual photomultiplier tubes (PMT). The size of a single GSO is 2.9mm×2.9 mm×15mm. The signals from four one-dimensional sharing detectors are fed to weighted summing circuits. They are digitized by 100 MHz free running analog to digital (A-D) converters and are used to calculate the position of gamma interaction. Coincidence was measured between this gamma imaging detector and a hand-held single gamma probe. Acquired data was transferred to a personal computer and displayed. Most spots correspond to GSOs were resolved in the position histogram. Spatial resolution was around 3mm when the distance between detectors is large and sensitivity was 0.1-0.2% when the single probe was 25mm from the imager surface. Images of phantoms were successfully obtained. We conclude developed coincidence imaging system has large FOV and easy to handle, reasonable spatial resolution and has potential to be a new instrument for nuclear medicine. Less

我们使用双光型型管（PMT）提出并测试1维块检测器。检测器由闪烁体块和双PMT组成。双重PMT在闪烁器块上光学耦合，并在一个维度上重叠。通过这种配置，可以将块检测器的闪光灯大小降低到一个方向的常规块检测器的一半，并且可以使用市售双PMT在跨轴和轴向方向以各向同性的空间分辨率获得。首先，我们测量最小配置的位置和能量响应。一个GSO块和两个双PMT。单个GSO的大小为2.9 mm x 2.9 mm x 20 mm。闪烁体在8×8矩阵中排列，多层光膜部分插入闪烁体之间，以获得分辨的位置响应。我们通过这种配置获得良好的位置和能量响应。接下来，我们制造一个1-D共享块检测器，其中有五个GSO块和6个双PM…更多TS。通过这种配置，我们还获得了合理的位置和能量响应。这些结果表明，所提出的1-D共享块检测器是开发高分辨率和低成本宠物系统的有希望的解决方案。我们也使用一维共享检测器开发了一个庞大的视野（FOV）重合成像系统。成像系统由四组一维共享块检测器和一个单个伽马探测器组成，并在这两个检测器之间进行巧合。一维共享检测器使用5个GSO块光学耦合到6双光电倍增管（PMT）。单个GSO的大小为2.9mm×2.9mm×15mm。来自四个一维共享检测器的信号被馈送到加权求和电路。它们通过对数字（A-D）转换器的100 MHz无运行类似物进行数字化，并用于计算伽马相互作用的位置。在该伽马成像探测器和手持单伽马探头之间测量了一致的巧合。获取的数据已将其传输到个人计算机并显示。大多数斑点对应于GSO，在位置直方图中解析。当检测器之间的距离较大时，空间分辨率约为3mm，当单个探针距成像仪表面25mm时，灵敏度为0.1-0.2％。成功获得了幻影的图像。我们包括开发的巧合成像系统具有较大的FOV，易于处理，合理的空间分辨率，并有可能成为核医学的新工具。较少的