Studies on the effect of wheat gluten diets in pregnant rats and improvement of its nutritional effect

小麦麸质饲料对妊娠大鼠的影响及其营养效果改善的研究

基本信息

批准号：
03680067
负责人：
MIZUKAMI Taiko
金额：
$ 1.34万
依托单位：
Nara Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1991
资助国家：
日本
起止时间：
1991 至 1992
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03680067/
关键词：
Pregnancy Wheat gluten L-lysine 妊娠時のタンパク質栄養リジンの補足効果

项目摘要

Influence of wheat gluten diets for pregnant rats on the maternal delivery and the growth of the progeny and supplementary effects of lysine to wheat gluten diets studied. Pregnant rats were fed on wheat gluten diets at protein level of 5%(G5), 10%(G10),20%(G20) and 30%(G30), and also the diets added with L lysine at level of 0.4%(G5+L), 0.5%(G10+L), 0.8%(G20+L), and 1.0%(G30+L), respectively. Control was set at 10% protein diet of purified whole egg protein. Every group of diet was converted to normal one during lactation.Although all groups of pregnant rats fed on the wheat gluten diets performed pregnancy and delivery, some in the groups of G5, G5+L and G10 showed neonatal death and stunted growth. The mortality rate of the progeny in G5 and G5+L groups during the period of lactation was higher than that of the control group. Supplementary effects of lysine were significantly observed in the groups fed on 10% or 20% wheat protein diets with lysine. Newborn pups of groups fed on 20% or 30% wheat protein diets with lysine and also on 30% wheat protein diet showed almost the same growth compared with the rats of the control group. The growth retardation of newborn pups caused by deficiency of protein during pregnancy can be recovered by normal diet during lactation. The progeny of groups fed on 10% wheat protein diets with lysine and also on 20% wheat protein diet showed almost the same growth compared with the progeny of the control group at 21st day after birth.

研究孕鼠小麦麸质饲料对母鼠分娩及子代生长的影响及赖氨酸对小麦麸质饲料的补充作用。孕鼠饲喂蛋白质水平为5%（G5）、10%（G10）、20%（G20）和30%（G30）的小麦麸质饲料，并添加0.4%赖氨酸（ G5+L), 0.5%(G10+L), 0.8%(G20+L), 和分别为1.0%(G30+L)。对照设定为 10% 纯化全蛋蛋白的蛋白质饮食。各组在哺乳期均转为正常饮食。虽然各组饲喂麦麸饲料的孕鼠均能妊娠分娩,但G5组、G5+L组和G10组中部分大鼠出现新生死亡和生长发育迟缓。 G5组和G5+L组哺乳期子代死亡率高于对照组。在饲喂含 10% 或 20% 小麦蛋白赖氨酸日粮的组中，观察到赖氨酸的补充作用显着。与对照组大鼠相比，饲喂 20% 或 30% 小麦蛋白赖氨酸饲料组以及饲喂 30% 小麦蛋白饲料组的新生幼仔表现出几乎相同的生长。妊娠期因蛋白质缺乏而引起的新生仔犬生长迟缓，哺乳期通过正常饮食即可恢复。饲喂含赖氨酸的 10% 小麦蛋白日粮和 20% 小麦蛋白日粮的组的后代在出生后第 21 天与对照组的后代几乎显示出相同的生长。