Studies in the effect of vegitable protein nutrition to pregnant rats on the growth of the young and improvement of its nutritional effect

孕鼠植物蛋白营养对仔鼠生长影响及改善其营养效果的研究

基本信息

批准号：
60580059
负责人：
MIZUKAMI Taiko
金额：
$ 1.28万
依托单位：
Nara Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1986
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60580059/
关键词：
Pregnancy Vegitable protein nutrition Rice Soy protein isolate Growth タンパク質の栄養効果

项目摘要

Influence of vegitable protein diets to pregnant rats on the growth of the young and additional effect of animal protein replacing a half of 5% and 10% protein diets were studied. Pregnant rats were fed such combinations of diets as follows: 5% protein diet groups were, Rice(A-1), Rice + Soy protein isolate(A-2), Rice + Egg albumin(A-3) and Rice + Milk casein(A-4).10% protein diet groups were, Rice + Soy protein isolate(B-1), Rice + Milk casein (B-2), Soy protein isolate(B-3) and Soy protein isolate + Egg albumin(B-4). Control was 20% protein diet of Pure egg protein.1. All groups(A-1 - A-4) of pregnant rats fed on 5% protein diets could perform pregnancy and delivery. A-1 and A-2 diets decreased neonatal survival, and mortality rate of the young during the period of lactation was about 17% in A-1 and about 73% in A-2 group. 5% protein diets significantly reduced body weight, organ weight, liver protein, RNA and DNA content at birth and caused persistent growth disturbance before the age of 49 days as compared with the control diet. A-3 and A-4 groups caused better growth than A-1 group and nutritional effect of protein in A-3 was comparatively higher than A-4 group.2. All groups(B-1 - B-4) of pregnant rats fed on 10% protein diets could maintain pregnancy. B-3 diet remarkably decreased survival rate of the neonates and all died in a few days after birth. B-4 diet lessened body weight and organ weight at birth, while almost all of neonates continued to grow up. The growth of the young fed on B-1 and B-2 diets were almost equivalent to that of the control. Nutritional effect of protein in B-2 diet was better than B-1 diet.

研究了植物蛋白饲料对怀孕大鼠幼鼠生长的影响以及动物蛋白替代一半5%和10%蛋白质饲料的附加效果。怀孕大鼠的饮食组合如下：5%蛋白质饮食组为大米（A-1）、大米+大豆分离蛋白（A-2）、大米+蛋清蛋白（A-3）和大米+牛奶酪蛋白(A-4).10%蛋白质饮食组为大米+大豆分离蛋白(B-1)、大米+牛奶酪蛋白(B-2)、大豆分离蛋白(B-3)和大豆分离蛋白+鸡蛋白蛋白(B-4)。对照为20%纯鸡蛋蛋白的蛋白质饮食。1．各组(A-1～A-4)饲喂5%蛋白质饲料的孕鼠均能妊娠分娩。 A-1和A-2饮食降低了新生儿的存活率，哺乳期幼仔的死亡率在A-1组中约为17%，在A-2组中约为73%。与对照饮食相比，5%蛋白质饮食显着降低了出生时的体重、器官重量、肝脏蛋白质、RNA和DNA含量，并在49天前造成持续的生长障碍。 A-3和A-4组比A-1组有更好的生长效果，A-3组蛋白质的营养效果也高于A-4组。2．各组(B-1～B-4)妊娠大鼠饲喂10%蛋白质饲料均能维持妊娠。 B-3饮食显着降低了新生儿的存活率，并在出生后几天内全部死亡。 B-4 饮食减轻了出生时的体重和器官重量，而几乎所有新生儿都继续成长。饲喂 B-1 和 B-2 日粮的幼仔的生长情况几乎与对照组相同。 B-2饮食中蛋白质的营养效果优于B-1饮食。