Evaluation of effect of dietary education for prevention of Type 2 diabetes

膳食教育预防2型糖尿病的效果评价

基本信息

批准号：
13680169
负责人：
WATANABE Mariko
金额：
$ 2.62万
依托单位：
Showa Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13680169/
关键词：
borderline diabetes mellitus blood sugar FFQW65 intervention study nutritional education semi-quantitative food frequency questionnaire manual modeling 血糖値栄養指導

项目摘要

OBJECTIVE: To assess in a randomized controlled trial the effectiveness of dietary education to prevent Type 2 diabetes for a high risk patients of Japanese male workers.RESEARCH DESIGN AND METHODS: This study was a prospective, randomized,controlled clinical trial of two levels of dietary education (DE) in persons with new DE program or conventional DE. The goals of the new DE were to attain and maintain optimal blood glucose levels, to modify nutrient intake and lifestyle as appropriate for prevention, to address individual nutritional needs, taking into consideration personal and cultural preferences as while respecting the individual wishes and willingness to change, and to promote healthy food intake pattern. The study hypothesis was that the new DE might reduce 10% of 2-h fasting plasma glucose (2-h FPG) with a 1 and 6 month DE during 1 year.Data were collected at entry to the study and 1 year after. Subjects were 141 male workers aged over 35 years in a metropolitan area of JAPAN who diagnosed as a high risk group of Type 2diabetes. The sample size was determined based on the information with significant level of 5%, power of 90%, and response rate around 90%. Primary endpoint was 10% reduction of 2-h FPG and improvements of dietary intakes were secondary outcome measures. The data was analyzed using analysis of covariance. Intention to treat was examined using logistic regression analysis.RESULTS: The subjects for the analysis were 170(91.9%) individuals, 88 for new DE, 82 for conventional DE. At 1 year, the new DE resulted in significance improvements in blood glucose control as indicated by 2-h FPG (<0.001) and dietary intakes (<0.001). As for ITT, no evidence was obtained for number of persons with 10% reduction of 2-h FPG.CONCLUSIONS: The new DE provided by dietitians using FFQ resulted in significant improvements and beneficial to high risk persons with Type 2 diabetes.

目的：通过随机对照试验评估膳食教育对日本男性工人高危患者预防 2 型糖尿病的有效性。研究设计和方法：本研究是一项前瞻性、随机对照临床试验，涉及两个水平的膳食接受新 DE 计划或传统 DE 的人员的教育 (DE)。新DE的目标是达到并维持最佳血糖水平，调整适合预防的营养摄入和生活方式，满足个人营养需求，同时考虑个人和文化偏好，同时尊重个人意愿和改变意愿，并提倡健康的饮食模式。研究假设是，新的 DE 可能会在 1 年内使 1 个月和 6 个月 DE 的 2 小时空腹血糖 (2-h FPG) 降低 10%。数据在研究开始时和一年后收集。研究对象为日本首都圈141名年龄超过35岁的男性工人，被诊断为2型糖尿病高危人群。样本量根据显着性水平为5%、功效为90%、响应率在90%左右的信息确定。主要终点是 2 小时 FPG 减少 10%，膳食摄入量的改善是次要结果指标。使用协方差分析来分析数据。采用logistic回归分析检查治疗意向。结果：分析对象为170例（91.9%），其中88例为新发DE，82例为常规DE。第 1 年时，新的 DE 显着改善了血糖控制，如 2 小时 FPG (<0.001) 和饮食摄入量 (<0.001) 所示。至于 ITT，没有获得 2 小时 FPG 降低 10% 的人数的证据。结论：营养师使用 FFQ 提供的新 DE 带来了显着改善，对 2 型糖尿病高危人群有益。