Evaluation of effect of dietary education for prevention of Type 2 diabetes

膳食教育预防2型糖尿病的效果评价

基本信息

批准号：
13680169
负责人：
WATANABE Mariko
金额：
$ 2.62万
依托单位：
Showa Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2001
资助国家：
日本
起止时间：
2001 至 2002
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13680169/
关键词：
borderline diabetes mellitus blood sugar FFQW65 intervention study nutritional education semi-quantitative food frequency questionnaire manual modeling 血糖値栄養指導

项目摘要

OBJECTIVE: To assess in a randomized controlled trial the effectiveness of dietary education to prevent Type 2 diabetes for a high risk patients of Japanese male workers.RESEARCH DESIGN AND METHODS: This study was a prospective, randomized,controlled clinical trial of two levels of dietary education (DE) in persons with new DE program or conventional DE. The goals of the new DE were to attain and maintain optimal blood glucose levels, to modify nutrient intake and lifestyle as appropriate for prevention, to address individual nutritional needs, taking into consideration personal and cultural preferences as while respecting the individual wishes and willingness to change, and to promote healthy food intake pattern. The study hypothesis was that the new DE might reduce 10% of 2-h fasting plasma glucose (2-h FPG) with a 1 and 6 month DE during 1 year.Data were collected at entry to the study and 1 year after. Subjects were 141 male workers aged over 35 years in a metropolitan area of JAPAN who diagnosed as a high risk group of Type 2diabetes. The sample size was determined based on the information with significant level of 5%, power of 90%, and response rate around 90%. Primary endpoint was 10% reduction of 2-h FPG and improvements of dietary intakes were secondary outcome measures. The data was analyzed using analysis of covariance. Intention to treat was examined using logistic regression analysis.RESULTS: The subjects for the analysis were 170(91.9%) individuals, 88 for new DE, 82 for conventional DE. At 1 year, the new DE resulted in significance improvements in blood glucose control as indicated by 2-h FPG (<0.001) and dietary intakes (<0.001). As for ITT, no evidence was obtained for number of persons with 10% reduction of 2-h FPG.CONCLUSIONS: The new DE provided by dietitians using FFQ resulted in significant improvements and beneficial to high risk persons with Type 2 diabetes.

目的：在一项随机对照试验中评估饮食教育对日本男性工人的高风险患者的2型糖尿病的有效性。研究和方法：这项研究是针对具有新的DE Program或常规DE的两个人的两种饮食教育（DE）的前瞻性，随机，对照临床试验（DE）。新DE的目标是实现和维持最佳的血糖水平，以适应预防的营养摄入和生活方式，以考虑个人和文化的偏好，以满足个人和文化的偏好，同时尊重个人的愿望和愿意改变，并促进健康食品摄入量。该研究假设是，新DE可能会在1年内使用1年和6个月的DE降低2-H禁食等离子体葡萄糖（2-H FPG）。受试者是日本大都市地区35岁以上的141名男性工人，被诊断为2型糖尿病类型的高风险群体。根据5％的显着水平，90％的功率和响应率约为90％的信息确定样本量。主要终点是2-H FPG降低10％，饮食摄入量的改善是次要结果指标。使用协方差分析对数据进行了分析。使用逻辑回归分析对治疗的意图进行了检查。分析：分析的受试者为170（91.9％）个个人，新DE为88，用于传统DE，为82。在1年时，新的DE导致了血糖控制的显着性改善，如2-H FPG（<0.001）和饮食摄入量（<0.001）所示。至于ITT，尚无证据表明降低2-H FPG的人数。结论：营养师使用FFQ提供的新DE导致了显着改善，对2型糖尿病的高风险患者有益。