Tissue-engineered finger bone/joints using biodegradable polymer

使用可生物降解聚合物的组织工程指骨/关节

• 批准号: 10671692
• 负责人: ISOGAI Noritaka
• 金额: $ 2.05万
• 依托单位: Kinki University School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671692/
• 关键词: polymer; tissue engineering; joint; osteoblast; Tissue engineering; 骨芽細胞

The study demonstrate the formation of small phalanges and whole joints from three types of bovine-cell sources transplanted onto biodegradable polymer matrices. The resulting structures had the shape and composition of human phalanges with joints.

该研究证明，将三种类型的牛细胞来源移植到可生物降解的聚合物基质上，形成小指骨和整个关节。由此产生的结构具有人类指骨和关节的形状和组成。

项目成果

Landis W, Isogai N, Vacanti J.: "Structure and chemical nature of phalanges formed by tissue engineering"Annals of biomedical engineering. 26. 140 (1998)

Landis W、Isogai N、Vacanti J.：“组织工程形成的指骨的结构和化学性质”生物医学工程年鉴。

磯貝,朝村,上石: "Tissue engineering"日本外科学会雑誌. 100. 539-543 (1999)

Isogai、Asamura、Kamiishi：“组织工程学”日本外科学会杂志 100. 539-543 (1999)。

ISOGAI, LANDIS, VACANTI: "Formation of phalangls a small joints of the finger by tissue engineering"J. Bone and Joint Surgery. 81A. 306-316 (1999)

ISOGAI、LANDIS、VACANTI：“通过组织工程形成指骨（手指的小关节）”J。