Mechanism of toxin synthesis using cultured poisonous mushroom

人工培养毒蘑菇合成毒素的机制

• 批准号: 10670380
• 负责人: GONMORI Kunio
• 金额: $ 2.3万
• 依托单位: Akita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10670380/
• 关键词: Mushroom poisoning; Cultivation; Magic mushroom; Growth factor; Analysis; HPLC; 毒きのこ; 幻覚きのこ; 毒成分

Several kind of mushrooms has strong toxicity to kill people. However, there have been only few reports of toxicological analysis on poisonous mushroom in forensic field. This study aimed to cultivate some poisonous mushrooms for the purpose of investigation and research in forensic toxicology. In our experiment the following mushrooms were cultivated, Pleurotus ostreatus, Lentinus edodes, Psilocybe cubensis, Amanita virosa, Lampteromyces japonicus and Gymnopilus spectabilis. Eventually the cultivation of Lyophyllum and Psilocybe cubensis resulted well-grown mushrooms. In the case of the Psilocybe cubensis, psilocybin and psilocin are the main hallucinogenic components. We observed the effect of storage on the concentration of these two hallucinogens. From harvesting the Psilocybe cubensis the freezing method provided the most valuable results to store mushrooms. A sample from a poisonous case suggested magic mushroom ingestion was analyzed. The mushroom was described as Psilocybe subcubensis. Recently the interest of the magic mushroom poisoning appears to be growing around the world. This research attempts to promote the investigation protocol for magic mushroom's cases.

几种蘑菇杀死人具有强大的毒性。但是，只有很少有关于法医领域有毒蘑菇毒理学分析的报道。这项研究旨在培养一些有毒的蘑菇，以进行法医毒理学研究和研究。在我们的实验中，培养了以下蘑菇，胸膜和lentinus edodes，psilocybe cubensis，amanita virosa，lampteromyces japonicus和Spectabilis Spectabilis。最终，Lyophyllum和psilocybe Cubensis的种植产生了良好的蘑菇。对于psilocybe cubensis，psilocybin和psilocin是主要的致幻成分。我们观察到储存对这两种致幻剂浓度的影响。通过收获psilocybe cubensis，冻结方法为储存蘑菇提供了最有价值的结果。分析了来自有毒病例的样本，建议分析魔术蘑菇摄入。蘑菇被描述为psilocybe subibensis。最近，魔术蘑菇中毒的兴趣似乎在世界各地增长。这项研究试图促进魔术蘑菇病例的调查方案。

项目成果

権守邦夫,吉岡尚文: "当教室で経験したきのこ中毒検査事例"秋田県救命救急研究会誌. 5. 74-78 (2001)

Kunio Gomori、Naofumi Yoshioka：“在我们的课堂上经历的蘑菇中毒测试案例”秋田县重症监护研究会杂志5. 74-78（2001）。

KUNIO GONMORI, NAOFUMI YOSHIOKA: "Poisoning Cases by Mushroom"Journal of Akia Emergency Medicine. 5. 74-78 (2001)

KUNIO GONMORI、NAOFUMI YOSHIOKA：“蘑菇中毒病例”Akia 急诊医学杂志。