Research on three dimensional imaging of lung and its pathologic basis.

肺部三维成像及其病理基础研究。

• 批准号: 07670998
• 负责人: ITOH Harumi
• 金额: $ 0.7万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670998/
• 关键词: Helical CT; 3D image; HRCT; Pleural Tag; Lymphatics; Pleura; ヘリカルCT; 三次元像; X線病理

The purpose of the study was to evaluate clinical usefulness of three-dimensional imaging of lung diseases obtained from helical X-ray CT (X-Vigor, Toshiba). The materials were lung carcinoma, mostly adenocarcinoma, operated. Three-dimensional CT images were correlated to macroscopic features of resected lung specimens. The results are as following.(1) Pleural retractionPleural retraction or pleural indentation was observed in 3D CT as several linear densities which converge on pleural surface. The shape of pleural convergence matched well to that of actual pleural retraction observed during operation. In addition, pleural convergence was reproduced well in the lung specimens inflated with air. In the central area of pleural convergence, isolated pleural surface attaching to tumor was covered by hyperinflated lung tissue. The presence of isolated pleural surface was diagnosed in conventional CT by linear edge of tumor which runs mostly parallel to chest wall.(2) Pleural NetworkSubpleural lymphatics were visualized as network pattern in 3D CT of inflated lung specimens. Pleural network was collections of polyhedral rings usually pigmented. Pleural network was hardly obsereved in clinical CT,however, in diseased condition where lymphatics are dilated, it became visualized.

本研究的目的是评估螺旋 X 射线 CT（X-Vigor，东芝）获得的肺部疾病三维成像的临床实用性。材料是手术后的肺癌，主要是腺癌。三维 CT 图像与切除肺标本的宏观特征相关。结果如下：(1)胸膜回缩在3D CT中观察到胸膜回缩或胸膜压痕，表现为多个线密度聚集在胸膜表面。胸膜会聚的形状与手术期间观察到的实际胸膜回缩的形状非常匹配。此外，在充气的肺样本中很好地再现了胸膜会聚。在胸膜会聚的中心区域，附着于肿瘤的孤立的胸膜表面被过度膨胀的肺组织覆盖。传统CT中通过肿瘤的线性边缘诊断孤立胸膜表面的存在，该边缘大多平行于胸壁。(2)胸膜网络胸膜下淋巴管在膨胀的肺标本的3D CT中可视化为网络模式。胸膜网络是通常着色的多面体环的集合。胸膜网在临床CT上几乎观察不到，但在淋巴管扩张的病变状态下，胸膜网变得可视化。

项目成果

浅本仁,他: "わが国における肺好酸球性肉芽腫症〜17症例についての臨床分析" 日本胸部疾患学会雑誌. 33 (12). 1372-1381 (1995)

Hitoshi Asamoto等：“日本肺嗜酸性肉芽肿病-17例临床分析”日本胸科疾病学会杂志33（12）1372-1381（1995）。

Johkoh, T., etal: "Perilobular Opacity on High-Resolution CT ; Pathologic Correlation" Jap J Clinical Radiology. 41(1). 119-127 (1996)

Johkoh, T. 等人：“高分辨率 CT 上的小叶周围混浊；病理相关性”Jap J 临床放射学。

Asamoto, H., etal: "Pulmonary Losinophilic Granuloma-Clinical Analysis of 17 Patients-" Jap J Thoracic Disease. 33(12). 1372-1381 (1995)

Asamoto, H. 等人：“肺嗜酸性肉芽肿 - 17 名患者的临床分析 -”Jap J Thoracic Medicine。

伊藤春海,他: "肺サルコイドーシスのHRCT〜肺野病変に関して〜" 医学のあゆみ. 178(1). 37-41 (1996)

Harumi Ito 等人：“肺结节病的 HRCT - 关于肺野病变”《医学史》178(1) (1996)。

浅本仁: "わが国における原発性肺胞蛋白症〜68症例の臨床的検討" 日本胸部疾患学会雑誌. 33. 835-845 (1995)

Hitoshi Asamoto：“日本原发性肺泡蛋白沉积症 - 68 例临床研究”日本胸科疾病学会杂志 33. 835-845（1995）。