Architecture of lung parenchyma and its implication to radiologic interpretation

肺实质的结构及其对放射学解释的意义

• 批准号: 14570846
• 负责人: ITOH Harumi
• 金额: $ 1.28万
• 依托单位: Faculty of Medical Sciences, University of Fukui
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570846/
• 关键词: lung parenchyma; image diagnosis; lung specimen; alveolar duct; alveolar dome; diffuse lung disease; HRCT; 肺胞; 肺細血管; 胸部写真; 肺胞道; 空間充填; 菱形12面体

The purpose of the study was to analyse architecture of lung parenchyma in order to promote further understanding of disease process extending in the lung. Stereomicroscopic, histologic and radiologic examinations were done in inflated and fixed lung specimens. The key structure of lung parenchyma was double sheets of alveoli separating two adjacent alveolar ducts. In this case, alveolar dome is hold in common between the double sheets. Pulmonary vessels were situated among the alveolar ducts. Adenocarcinoma is disease where cancer extends continuously along the double alveolar sheets. Pulmonary tuberculosis is typical in which alveolar ducts are filled by exdudates. Sarcoisosis is characterized by guranolomas formed along pulmonary vessels. These diseases are well understood with new knowledges about lung parenchyma gotten by this study. This study provided morphologic bases of evaluating normal and abnormal X-ray images.

该研究的目的是分析肺实质的结构，以促进进一步了解肺部疾病过程。对充气和固定的肺标本进行立体显微镜、组织学和放射学检查。肺实质的关键结构是分隔两个相邻肺泡管的双层肺泡。在这种情况下，牙槽顶在双层片之间是共同的。肺血管位于肺泡管之间。腺癌是癌症沿着双肺泡片连续延伸的疾病。肺结核是典型的肺泡管被渗出物填充的疾病。肉瘤病的特征是沿肺血管形成瓜拉诺洛瘤。通过这项研究获得了关于肺实质的新知识，这些疾病得到了很好的理解。这项研究为评估正常和异常X射线图像提供了形态学基础。

项目成果

伊藤春海: "胸部HRCTの読影と考え方"治療. 85・6. 1847-1853 (2003)

伊藤晴美：“胸部HRCT的解释和概念”治疗85・6（2003）。

伊藤春海: "HRCT続影のための肺既存構造-肺実質を中心に-"日本胸部臨床. 61・増刊号. S25-S36 (2002)

Harumi Ito：“HRCT 后续成像的现有肺结构 - 关注肺实质 -”日本胸部诊所 61/S25-S36（2002 年）。

伊藤春海: "HRCTによる特発性肺線維症の診断と鑑別"日本医師会雑誌. 128・2. 213-217 (2002)

Harumi Ito：“通过HRCT诊断和鉴别特发性肺纤维化”日本医学会杂志128・2（2002年）。

Nakatsu M, Hatabu H, Morikawa K, Uematsu H, Ohno Y, Nishimura K, Nagai S. Izumi T, Konishi J. Itoh H: "Large Coalescent Parenchymal Nodules in Pulmonary Sarcoidosis :"Sarcoid Galaxy"Sign"Am J Roentgenol. 178・6. 1389-1393 (2002)

Nakatsu M、Hatabu H、Morikawa K、Uematsu H、Ohno Y、Nishimura K、Nagai S. Izumi T、Konishi J. Itoh H：“肺结节病中的大聚结实质结节：“结节星系”标志”Am J Roentgenol 178。・6。1389-1393（2002）

伊藤春海: "HRCTによる特発性肺線維症の診断と鑑別"日本医師会雑誌. 128・2. 213-217 (2001)

Harumi Ito：“通过HRCT诊断和鉴别特发性肺纤维化”日本医学会杂志128・2（2001年）。