Analysis of cerebral functions stimulated by mastication on malocclusions by using PET

PET分析咬合不正咀嚼刺激脑功能

• 批准号: 07838003
• 负责人: MITANI Hideo
• 金额: $ 1.47万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07838003/
• 关键词: mastication; cerebral blood flow; positron emission tomography; malocclusions; skeletal pattern; Rolandic area; rCBF; normal occlusions; 不正咬合

The aim of this study was to obtain basic data regarding the relationships between cerebral functions stimulated by mastication and morphological features of occlusion.Six normal male volunteers, aged 21 to 32 years were included in this study. Occlusal and skeletal features of all subjects were examined by study models and cephalograms. Cerebral blood flow at rest and chewing gum base were measured with ^<15>O-labeled water by using Positron emission tomography. The regions of interest on cerebral blood flow image were drawn referring brain atlas. The change of blood flow at each regions were calculated.Changes of regional cerebral blood flow (rCBF) by chewing gum were widely varied. In normal occlusions with harmonious relationship of jaws, rCBF increasing were generally demonstrated on Rolandic area, insula and cerebellum. On the other hand, in malocclusions with any dental or skeletal problems, region and volume of increasing cerebral blood flow were different from that in normal occlusions, and rCBF were not almost increased by chewing gum on Rolandic area and insula in anyone with malocclusons.Results may be indicated that cerebral function stimulated by mastication are related with features of occlusion and skeletal pattern.

这项研究的目的是获得有关咀嚼和闭塞形态特征刺激的脑功能之间关系的基本数据。这项研究包括21至32岁的正常男性志愿者。通过研究模型和头部图检查了所有受试者的咬合和骨骼特征。使用正电子发射断层扫描用 ^<15> o标记的水测量静止和咀嚼口香糖基碱的脑血流。绘制了脑血流图像感兴趣的区域，引用了大脑图集。计算了每个区域的血流变化。咀嚼口香糖的区域脑血流（RCBF）的改变变化。在正常的闭塞与颌骨和谐关系的正常遮挡中，ROLANDIC区域，岛状和小脑通常证明了RCBF的增加。另一方面，在具有任何牙齿或骨骼问题的层囊肿中，脑血流增加的区域和数量与正常闭塞的区域不同，而在Rolandic地区咀嚼口香糖和Malocclusons的任何人，RCBF几乎不会增加RCBF。可以表明，咀嚼刺激刺激的大脑功能与遮挡和骨骼模式有关。

项目成果

佐藤亨至、三谷英夫、マルコAメヒア、伊藤正敏: "ポジトロンCTによる咀嚼時脳血流動態と咬合との関連" 日本矯正歯科学会雑誌. 55. 300-310 (1996)

Toruji Sato、Hideo Mitani、Marco A. Mejia、Masatoshi Ito：“使用正电子 CT 观察咀嚼过程中脑血流动力学与咬合之间的关系”日本正畸学会杂志 55. 300-310 (1996)。

佐藤 亨至、三谷 英夫、マルコAメヒア、伊藤 正敏: "ポジトロンCTによる咀嚼時脳血流動態と咬合との関連" 日本矯正歯科学会雑誌. 55巻・4号. 300-310 (1996)

Toruji Sato、Hideo Mitani、Marco A. Mejia、Masatoshi Ito：“使用正电子 CT 观察咀嚼过程中脑血流动力学与咬合之间的关系”，日本正畸学会杂志，第 55 卷，第 4. 300-310 期（1996 年）。

Sato K., Mitani, H., Mejia M.A.and Ito M.: "Relationship between regional cerebral bllod flow during mastication and morphological features of occlusion" J.Jpn.Orthod.Soc.55. 300-310 (1996)

Sato K.、Mitani, H.、Mejia M.A. 和 Ito M.：“咀嚼过程中局部脑血流与咬合形态特征之间的关系”J.Jpn.Orthod.Soc.55。