Mobile System for Functional Near-Infrared Spectroscopy (fNIRS)

功能性近红外光谱移动系统 (fNIRS)

• 批准号: 527194510
• 金额: --
• 依托单位: Eberhard Karls Universität Tübingen
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/527194510?language=en
• 关键词: Mobile; System; Functional; Near; Infrared

The research focus of the applying department is the investigation of the fundamental mechanisms involved in the development and maintenance of pathological eating behavior and body image disorder. Imaging methods provide insights into the neural correlates of such mechanisms and thus contribute significantly to a fundamental understanding. In order to realize the research ambitions of the department, neuroimaging and training studies in outpatient settings will continue to be carried out in particular. In recent years, this core competence has been strengthened in the growing working group. For the department's research projects, a mobile system for functional near-infrared spectroscopy (fNIRS) is needed, which can flexibly and in different scenarios investigate cortical activations. Due to rapid hardware developments in fNIRS research, mobile devices are now available that allow for studies on patients in outpatient settings and in economically valid scenarios, e.g. during exposure or eating-related tasks. In particular, the correction for extracerebral signals, which are only made possible by newer devices with short-distance channels, is noteworthy. This keeps research competitive in the long-term and results are not confounded by motor artifacts. The requested device is compatible with other relevant methods of the research group, particularly tDCS, EEG, eye-tracking, and VR. A minimum number of 32 high-quality optode pairs (32 sources, 32 detectors) is required to cover the cortical areas that are relevant to current and future research projects. A compatible multichannel stimulator is additionally requested that will be used in combination with fNIRS, but which is distinct from other neurostimulation projects. The overall system must be suitable and approved for research on adult and pediatric patients. In Tübingen, there is already a lot of experience with fNIRS in various departments, and a network for methodological and content exchange. In 2021, researchers of the department, together with colleagues from cognitive neuropsychology, the clinic for psychiatry and psychotherapy, as well as the institute for diabetes research and metabolic diseases, organized an international, intramural-funded fNIRS summer school. Close networking between the departments and joint research projects strengthen the methodological expertise and social contribution of the location and its networking with international partners. Therefore, the acquisition of this mobile fNIRS system will significantly contribute to the department's research capabilities and allow for more flexible and efficient research and collaboration.

应用部门的研究重点是对患者饮食行为和身体形象障碍的发展和维护涉及的基本机制的投资。成像方法提供了对这种机制神经相关物的见解，因此对基本理解产生了重大贡献。为了实现该部门的研究野心，将继续在门诊环境中进行神经影像学和培训研究。近年来，在不断发展的工作组中，这种核心能力得到了增强。对于该部门的研究项目，需要用于功能性近红外光谱的移动系统（FNIRS），这可以灵活，并且在不同的情况下研究皮质激活。由于FNIRS研究中的快速硬件开发，现在可以使用移动设备，可以在门诊环境和经济有效的情况下进行研究，例如在暴露或与饮食有关的任务中。特别是，值得注意的是，脑外信号的校正仅由具有短距离通道的较新设备实现。这使得长期的研究具有竞争力，并且结果不会被运动伪像的混淆。所请求的设备与研究组的其他相关方法兼容，尤其是TDC，EEG，Eye-Tracking和VR。至少需要32个高质量的频道对（32个来源，32个检测器）才能覆盖与当前和未来研究项目相关的皮质区域。另外要求兼容的多通道刺激器与FNIRS结合使用，但与其他神经刺激项目不同。整个系统必须适合对成人和小儿患者进行研究。在Tübingen，各个部门已经有很多FNIRS的经验，以及用于方法和内容交换的网络。 2021年，该系的研究人员与认知神经心理学的同事，精神病学和心理疗法诊所以及糖尿病研究和代谢疾病研究所一起组织了一项国际，壁内资助的FNIRS FNIRS暑期学校。部门与联合研究项目之间的密切联系增强了该地点的方法论专业知识和社会贡献及其与国际合作伙伴的网络。因此，收购此移动FNIRS系统将极大地促进该部门的研究能力，并提供更灵活，更有效的研究和协作。