ANALYSIS OF TEMPERATURE CHARACTERISTIC OF SYSTOLE IN HIBERNATOR WITH ULTRASONIC TOMOGRAPHY

超声断层扫描分析冬眠器心搏温度特性

• 批准号: 07670086
• 负责人: OHWATARI Nobu
• 金额: $ 1.47万
• 依托单位: NAGASAKI UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07670086/
• 关键词: HIBERNATOR; CARDIO FUNCTION; ACUTE COLD EXPOSURE; ULTRASONIC TOMOGRAPH; HYPOTHERMIA; 冬眠動物,; 心収縮特性; 超音波画像; 寒冷耐性; 温度特性; 寒冷ふるえ熱産生; 非ふるえ熱産生

In this study, I examined temperature characteristic of cardiac function with ultrasonic tomograph by B- and M-modes under a course of hypothermia at 8ﾟC caused by acute cold exposure hibernator (Syrian hamster). I compared it with experimental findings of non-hibernator (Wistar rat) as control group.In electrocardiography (ECG), complete atrioventricular block was observed at abdominal temperature (Tab) of 19ﾟC with non-hibernator, but atrio-ventricular block of the first stage that P-Q interval got longer at 10ﾟC was recognized in hibernator. Furthermore, Tab was 18.11 <plus-minus> 0.83ﾟC in non-hibernator, then ECG disappeared. But the phenomenon wasn't observed to depressed Tab of 7.22 <plus-minus> 0.31ﾟC in hibernator. Movement of myocardium of left ventricle became slow when became less than 21.8ﾟC with non-hibernator in ultrasonic tomography of heart stroke. Speed of mitral valve also observed slowly, so degradation of cardiac output was suggested. On the other hand, similar development was found by 9.8ﾟC in hibernator. As examination subject after now, it couldn't measure a clear ultrasonic tomography by shivering of cold exposure early stIn non-hibernation, cardiac function of hibernator was maintained under hypothermia, the significant cold tolerance was provided as well as in hibernation.

在这项研究中，我在急性冷暴露冬眠（叙利亚仓鼠）引起的8°C下，通过B型和M模型检查了心脏功能的温度特征。我将其与非启动器（Wistar大鼠）的实验发现作为对照组进行了比较。在心电图（ECG）中，在19 c c的腹部温度（TAB）中观察到完全室内的室内障碍物（TAB），但具有非透纤维，但在10阶段的p-q间隔在10级时识别为p-q间隔的时间更长的时间。此外，在非纤维化器中，TAB为18.11 <plus-minus> 0.83 c，然后ECG消失了。但是，没有观察到这种现象是在冬眠中抑制7.22 <plus-minus> 0.31 c的标签。左心室的心肌运动在超声层中的心脏中风超过21.8 c时变慢。二尖瓣的速度也缓慢观察到，因此提出了心脏输出的降解。另一方面，在冬眠中发现了9.8°C的类似发展。作为检查对象之后，它可以通过颤抖的早期氏症来测量清晰的超声断层扫描，在低温下保持冬眠的心脏功能，提供了明显的冷耐受性以及冬眠。

项目成果

Nobu Ohwatari: "A new approach to analysis of human sweating." Experientia. 52. 131-135 (1996)

Nobu Ohwatari：“一种分析人类出汗的新方法。”

Nobu Ohwatari: "A field study of telemetry-recording of the body temperature in wild Mongolian pikas." Trop Med. 37(3). 93-98 (1995)

Nobu Ohwatari：“对野生蒙古鼠兔体温遥测记录的实地研究。”

Ohwatari N: "Body temperature and metabolism." Ed by Nagasaka T and Milton AS,IPEC inc.,Tokyo, 376 (1995)

Ohwatari N：“体温和新陈代谢。”

Pleschka K,Schnecko A,Lemmer B,Ohwatari N and Ntirnberger F: "In vitro stimulation of adenylyl cyclase in the hippocampus, cortex and cerebellum of euthermic and hibernating hamsters" In Adaptations to the Cold, Ed Geiser F,Hulbert A J and Nicol S C,Unive

Pleschka K、Schnecko A、Lemmer B、Ohwatari N 和 Ntirnberger F：“体外刺激恒温和冬眠仓鼠海马、皮质和小脑中的腺苷酸环化酶”，《适应寒冷》，Ed Geiser F、Hulbert A J 和 Nicol SC

Nobu Ohwatari: "Behavioral thermoregulation of Pika-Thermal insulation of fur and skin-" Parmacolgy of Thermoregulation. 10(in press). (1996)

Nobu Ohwatari：“鼠兔的行为温度调节-皮毛和皮肤的隔热-”温度调节的Parmacolgy。