Micro CT image processing for high contrast images

高对比度图像的显微 CT 图像处理

• 批准号: 523215-2018
• 负责人: Tamimi, Faleh
• 金额: $ 1.82万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=666460
• 关键词: Micro; CT; image; processing; contrast

Trikon Technologies (Montreal) specializes in nondestructive testing and 3D imaging, and is interested in**expansion from engineering and materials sciences towards life sciences. Effective analysis of biological**objects requires special expertise in bio-image processing because of their high structural complexity and more**delicate nature of such objects. This project aims to enrich the company's portfolio to include bio-imaging.**Using advanced instrumentation at Trikon, academic partners at McGill University will analyze trabecular**bone texture that reflects functional adaptation to biomechanical requirements. A series of human bones that**have been naturally subjected to different loading conditions will be scanned using X-ray tomography at the**company's facilities. A sequence of image processing steps will be established and optimized (i.e., filtering,**segmentation, structure shape and topology analysis, machine learning-based feature extraction and**quantification). This sequence of analysis will be unified into an automated protocol (macro); automation of**processing routines by writing macros is important in reducing hands-on time for staff, optimizing**computational processing time, and guaranteeing reproducibility. This work on bone texture analysis will**serve as a training platform for acquiring expertise by Trikon applications specialists. Optimized and**automated image processing protocols resulting in quantitative analysis of the data will become a unique**company capability. Future applications of this versatile characterization protocol include (but are not limited**to) physical anthropology, archaeology, forensics, zoology, botany, orthopaedic medicine and dentistry, and**even civil engineering for development of biomimetic materials. Trikon specialists will expand their industrial**niche by investing in high-end technology and data processing that will help to define determinants of skeletal**adaptation by the academic partner.

Trikon Technologies（蒙特利尔）专注于无损检测和 3D 成像，并有兴趣**从工程和材料科学扩展到生命科学。生物**对象的有效分析需要生物图像处理方面的特殊专业知识，因为此类对象的结构高度复杂性和更**微妙的性质。该项目旨在丰富公司的产品组合，将生物成像纳入其中。**麦吉尔大学的学术合作伙伴将使用 Trikon 的先进仪器来分析小梁**骨纹理，以反映对生物力学要求的功能适应。一系列在自然条件下承受不同负载条件的人体骨骼将在**公司的设施中使用 X 射线断层扫描进行扫描。将建立和优化一系列图像处理步骤（即过滤、**分割、结构形状和拓扑分析、基于机器学习的特征提取和**量化）。该分析序列将统一为自动化协议（宏）；通过编写宏实现处理例程的自动化对于减少员工的操作时间、优化计算处理时间和保证可重复性非常重要。这项骨纹理分析工作将**作为 Trikon 应用专家获取专业知识的培训平台。优化和**自动化的图像处理协议导致数据的定量分析将成为独特的**公司能力。这种多功能表征协议的未来应用包括（但不限于）体质人类学、考古学、法医学、动物学、植物学、骨科医学和牙科，甚至用于开发仿生材料的土木工程。 Trikon 专家将通过投资高端技术和数据处理来扩大他们的工业**利基市场，这将有助于学术合作伙伴确定骨骼**适应的决定因素。