International Data Base for Human Brain Function

国际人脑功能数据库

基本信息

批准号：
09044250
负责人：
FUKUDA Hiroshi
金额：
$ 3.65万
依托单位：
TOHOKU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for international Scientific Research
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09044250/
关键词：
Computerized Brain Atlas human brain function image database Anatomical Normalization PET MRI

项目摘要

1. Development and Evaluation of the Computerized Brain Atlas SystemWe validated the anatomical precision of spatial normalization with the Elastic Transformation System which has developed by Zilles's group with our collaboration. We found that this system shows high effectiveness in spatial normalization procedure compared with other systems, indicating that it can be used not only for positorn emission tomography (PET) activation studies but for functional magnetic resonance imaging (MRI) studies.2. Functional Brain Mapping of Cognitive and Motor FunctionRoland's group and our group participated this project. We used PET to investigate functional brain areas of humans involved in many kinds of cognitive or motor tasks. The results obtained are used as contents of the brain function database which has been developing by our group.3. Development of International Brain Anatomy DatabaseWe and Evans's group had a meeting in Montreal, and have agreed to create comparable international brain anatomy database with Zilles's group. We have decided to correct 300 3D-brain MRI of healthy subjects for each group, and to perform inter-ethnic comparisons using spatial normalization technique develped by Evans's group. Our group already corrected 150 brain MRIs, and we have estimated standard brain anatomy of the Japanese population of different age group from this data.

1。对计算机化大脑Atlas Systemwe的开发和评估验证了Zilles集团通过我们的协作开发的弹性转换系统的空间标准化的解剖学精度。我们发现，与其他系统相比，该系统在空间归一化过程中表现出很高的有效性，这表明它不仅可以用于正面的发射断层扫描（PET）激活研究，还可以用于功能性磁共振成像（MRI）研究。2。认知和运动功能界组的功能性脑映射以及我们的小组参与了该项目。我们用PET研究了参与许多认知或运动任务的人类的功能性大脑区域。获得的结果用作我们组开发的大脑功能数据库的内容3。国际大脑解剖数据库和埃文斯小组在蒙特利尔举行了会议，并同意与Zilles的小组创建可比的国际大脑解剖数据库。我们已决定为每组健康受试者的300个3D-Brain MRI纠正300个3D-Brain MRI，并使用Evans组DEVEL的空间标准化技术进行种族间比较。我们的小组已经纠正了150个脑部MRI，我们已经从该数据中估计了不同年龄段的日本人群的标准脑解剖结构。