Neuromuscular mechanisms governing knee joint biomechanics during normal gait

正常步态下控制膝关节生物力学的神经肌肉机制

• 批准号: 418025-2013
• 负责人: Hunt, Michael
• 金额: $ 2.11万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=596215
• 关键词: Neuromuscular; mechanisms; governing; knee; joint

During ambulation, the joints of the lower limb - the knee in particular - must withstand large forces exerted onto them to permit the smooth and efficient continuation of forward progression. While structures such as bones and ligaments can assist in the distribution of these forces, our muscles are believed to be primarily responsible for absorption of these forces and to protect the joints over time. Previous researchers have attempted to model the distribution of forces throughout the knee joint during walking, though these models are limited in their accuracy due to a lack of information regarding the anatomy of the lower limb during weight-bearing activities and the difficulty in isolating the effects of muscle activation on movement parameters. The proposed mechanistic research program will provide new information about not only the relationships between aspects of muscle function and loading at the knee joint during walking, but the neuromuscular control of normal human movement.

在行走过程中，下肢的关节（尤其是膝盖）必须承受施加在其上的巨大力，以允许平稳有效地继续向前前进。虽然骨骼和韧带等结构可以帮助分布这些力，但我们的肌肉被认为主要负责吸收这些力并随着时间的推移保护关节。先前的研究人员曾尝试对步行过程中整个膝关节的力分布进行建模，但由于缺乏有关负重活动期间下肢解剖结构的信息以及难以隔离影响，这些模型的准确性受到限制肌肉激活对运动参数的影响。拟议的机械研究计划不仅将提供有关行走过程中肌肉功能和膝关节负荷之间关系的新信息，而且还将提供有关正常人体运动的神经肌肉控制的新信息。