Development of Subtraction CT Technique for Detection of Lung Nodules on Low-Dose CT

低剂量CT肺结节减影CT技术的发展

• 批准号: 14570890
• 负责人: ISHIDA Takayuki
• 金额: $ 1.6万
• 依托单位: HIROSHIMA INTERNATIONAL UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570890/
• 关键词: Lung CT; Lung cancer; Computer-aided diagnosis; Lung cancer screening; Pulmonary nodules

Low-dose CT is sensitive in the detection of early lung cancer, however, the interpretation of a large number of CT images is time consuming for radiologists. Therefore, we have developed a subtraction CT technique to assist radiologists for their detection of small lung nodules. In this scheme, the "mask image" for a given section was obtained by a 3 dimensional morphological filtering and line enhancement filtering. The subtraction CT images were obtained by subtracting the warped mask images, which were obtained by iterative image warping technique, from the corresponding CT images. For further reduction of artifacts due to vessels, we employed a line enhancement filter. The extracted line patterns in the target section image were added to the mask image. Thus the artifacts due to vessels in the subtraction image could be eliminated. The subtraction CT images can clearly enhance small lung nodules. The subtraction CT image could be useful for the detection of early lung cancer.

低剂量CT对检测早期肺癌的检测很敏感，但是，放射科医生对大量CT图像的解释很耗时。因此，我们开发了一种减法CT技术，以协助放射科医生检测小肺结节。在此方案中，给定截面的“掩码图像”是通过3维形态滤波和线增强滤波获得的。通过从相应的CT图像中减去通过迭代图像翘曲技术获得的扭曲的掩模图像来获得减法CT图像。为了进一步减少由于血管引起的工件，我们采用了线条增强滤波器。目标截面图像中提取的线模式添加到掩模图像中。因此，可以消除由于减法图像中的血管引起的伪影。减法CT图像可以清楚地增强小肺结节。减法CT图像可能可用于检测早期肺癌。

项目成果

石田隆行, 桂川茂彦, Feng Li, 曾根脩輔, 土井邦雄: "早期肺がんのためのサブトラクションCT法"電子情報通信学会・信学技報. MI2002-60(2002-09). 23-26 (2002)

Takayuki Ishida、Shigehiko Katsurakawa、Feng Li、Shusuke Sone、Kunio Doi：“早期肺癌的减影CT方法”MI2002-60(2002-09)。

石田隆行, 桂川茂彦, 士井邦雄: "胸部ヘリカルCT画像における早期肺がん検出のための経時的差分CT技術の開発"日本放射線技術学会誌. (予稿集). 264 (2003)

Takayuki Ishida、Shigehiko Katsurakawa、Kunio Shii：“胸部螺旋 CT 图像中早期肺癌检测的时间差分 CT 技术的发展”，日本放射线技术学会杂志（论文集）264（2003 年）。

石田隆行, 桂川茂彦, Feng Li, 曾根脩輔, 土井邦雄: "Development of Subtraction CT Technique for Detection of Lung Nodules on Low-Dose CT"Radiology (2002 Scientific Program). 225(P). 713 (2003)

Takayuki Ishida、Shigehiko Katsurakawa、Feng Li、Shusuke Sone、Kunio Doi：“低剂量 CT 检测肺结节的减影 CT 技术的发展”放射学（2002 年科学计划）225（P）。

阿部裕之, 石田隆行, Feng Li, 桂川茂彦, 曾根脩輔, 土井邦雄: "Effect of Temporal Subtraction Images on the Detection of Lung Cancer on Low-Dose CT"Radiology (2003 Scientific Program). (Program). 262 (2003)

Hiroyuki Abe、Takayuki Ishida、Feng Li、Shigehiko Katsurakawa、Shusuke Sone、Kunio Doi：“时间减影图像对低剂量 CT 肺癌检测的影响”放射学（2003 年科学计划）262（计划）。 ）

阿部裕之, 石田隆行, Feng Li, 桂川茂彦, 曾根脩輔, 土井邦雄: "Effect of Temporal Subtraction Images on the Detection of Lung Cancer on Low-Dose CT"Radiology (2003 Scientific Program). Program. 262 (2003)

Hiroyuki Abe、Takayuki Ishida、Feng Li、Shigehiko Katsurakawa、Shusuke Sone、Kunio Doi：“时间减影图像对低剂量 CT 检测肺癌的影响”放射学（2003 年科学计划）。