Degradation of Adhesive Restorations and Release of Endocrine Disrupter

粘合修复物的降解和内分泌干扰物的释放

• 批准号: 11470401
• 负责人: SANO Hidehiko
• 金额: $ 3.39万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11470401/
• 关键词: Ahesion; Degradation; Endocrine Disruptor; 内分泌撹乱物質; 修復物の耐久性; 象牙質接着; コンポジットレジン; 修復物の耐

The results of the research project reviled that the adhesive interface degraded over time. Moist bonding systems showed greater degradation with the extraction of resin within the hybrid layer and depletion of collagen fibrils compared to self-etching systems both in vivo and in vitro. Release of endocrine disrupter from resins were undetectable from both short- and long-term experiment in vivo.

该研究项目的结果表明，粘合界面会随着时间的推移而退化。与体内和体外的自蚀刻系统相比，湿粘合系统随着混合层内树脂的提取和胶原纤维的消耗而表现出更大的降解。从短期和长期体内实验中均检测不到树脂释放的内分泌干扰物。

项目成果

Takahashi, A.: "Effect of mechanical properties of adhesive resins on bond strength to dentin"Dental Materials. 18. 263-268 (2002)

Takahashi, A.：“粘合树脂机械性能对牙本质粘合强度的影响”牙科材料。

Hashimoto M., Ohno H., Kaga M., Endo K., Sano H., Oguchi H.: "The Extent ot wshich resin can infiltrate dentin by aceone-based adhesives"Journal of Dental Research. 81. 74-78 (2002)

Hashimoto M.、Ohno H.、Kaga M.、Endo K.、Sano H.、Oguchi H.：“树脂可以通过基于丙酮的粘合剂渗透牙本质的程度”牙科研究杂志。

M.Hashimoto, H.Ohno, M.kaga K.Endo, H.Sano and H.Oguchi: "In vivo degradation of resin-dentin bonds in humans over 1 to 3 year"Journal of Dental Research. Vol 79 No.6. 1385-1391 (2000)

M.Hashimoto、H.Ohno、M.kaga K.Endo、H.Sano 和 H.Oguchi：“1 至 3 年内人体树脂-牙本质键的体内降解”《牙科研究杂志》。

H. Sano, T. Yoshikawa, P.N.R. Pereira, N. Kanemura, M. Morigami, J. Tagami, Dhpahley: "Long-term Durability of Dentin Bonds Made with a self-etching Primer, in vivo"Journal of Dental Research. Vol.78 No.4. 906-911 (1999)

H. 佐野、T. 吉川、P.N.R.

Hashimoto, M: "The extent to which resin can infiltrate dentin by ace tone-based adhesives"Journal of Dental Research. 18. 74-78 (2002)

Hashimoto, M：“树脂通过基于 acetone 的粘合剂渗透到牙本质的程度”《牙科研究杂志》。