Development of advanced ESR crystallographic system (software and hardware) and ESR imaging system and these applications

先进ESR晶体学系统（软件和硬件）和ESR成像系统的开发及其应用

• 批准号: 10555005
• 负责人: KOBAYASHI Tadashi
• 金额: $ 8.51万
• 依托单位: Oita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-10555005/
• 关键词: Electron Spin Resonance; ESR; Spin Hamiltonian; Crystal; Goniometer; MRI; CT; Dielectric Resonator; スピン ハミルトニアン; 画像再構成; スピン ハミルトニア; 結晶解析システム; 応力印加; ESR-CT

We have been engaging in the development of the 30 ESR apparatuses (hardware) and the computer analysis system of ESR crystallography (software). In the former case, several universal and particular ESR sample cavities, several 2-circle and 3-circle ESR goniometers, ESR apparatuses for applying uniaxial stress and electric field and so on have been developed so far. In the latter case, the direct search method for determining spin Hamiltonian parameters, the simplex method to refine the spin Hamiltonian parameters, the interface soft between X-ray and ESR crystallographic systems, for example, the program to draw the ESR tensors in the figure of crystal structure by using ORTEP and so on have been constructed.On the other hand, several ESR imaging apparatuses adopting a localized (ESR) signal detective method or a magnetic field gradient one have been developed. The former is the X-band ESR imaging (ESR-CT) apparatus with a pin-hole TE102 mode cavity and a rapid scan coils. The latter are the ESR imaging apparatus with a TM1 10 mode cavity and 3-dimentional field gradient coils (anti-Hclmholtz coils and Anderson coils pairs) and the high resolution ESR microscope with Zupancic MRI coils and dielectric resonator and so on. Using these apparatuses, ESR imaging of melanin in mouse B16 melanoma was observed for the first time. The 3-dimentional ESR dosimetry system has been constructed by using the ESR imaging plate made of alanine or sucrose.

我们一直致力于30台ESR仪器（硬件）和ESR晶体学计算机分析系统（软件）的开发。目前已研制出多种通用型和专用型ESR样品腔、多种2环和3环ESR测角仪、施加单轴应力和电场的ESR装置等。在后一种情况下，确定自旋哈密顿参数的直接搜索方法、细化自旋哈密顿参数的单纯形法、X射线和ESR晶体系统之间的接口软件，例如图中绘制ESR张量的程序另一方面，已经开发了几种采用局域(ESR)信号检测方法或磁场梯度方法的ESR成像装置。前者是带有针孔TE102模腔和快速扫描线圈的X波段ESR成像（ESR-CT）设备。后者是带有TM1 10模腔和三维场梯度线圈（反Hclmholtz线圈和Anderson线圈对）的ESR成像装置以及带有Zupancic MRI线圈和介质谐振器的高分辨率ESR显微镜等。使用这些设备，首次观察到小鼠 B16 黑色素瘤中黑色素的 ESR 成像。利用丙氨酸或蔗糖制成的ESR成像板构建了三维ESR剂量测定系统。

项目成果

Tadashi Kobayashi: "THe epock-making techniques to develop newly invented analytical instruments and functional devices and its applied examples : in the field of ESR crystallography and ESR imaging region"Advances in ESR Applications. 16. 24-29 (2000)

小林正：“开发新发明的分析仪器和功能装置的划时代技术及其应用实例：在ESR晶体学和ESR成像领域”ESR应用的进展。

小林 正: "電子スピン共鳴イメージング(ESR-CT)装置の開発と自動計測(講演番号4010)" 第41回 自動制御連合講演会(大分市コンパルホール). (1998)

小林正：“电子自旋共振成像（ESR-CT）设备的开发和自动测量（演讲编号4010）”第41届自动控制联盟演讲（大分市仁宝礼堂）（1998年）。

Tadashi Kobayashi: "Ferroelastic domain boundary of LaNbO_4"Journal of the Korean Physical Society. 32. S750-S751 (1998)

小林正：“LaNbO_4 的铁弹性域边界”韩国物理学会杂志。

Tadashi Kobayashi: "Ferroelastic Domain Boundary of LaNbO_4" J.Korean Phys.Soc.32. S750-S751 (1998)

Tadashi Kobayashi：“LaNbO_4 的铁弹性域边界”J.Korean Phys.Soc.32。

Tadashi Kobayashi: "Landau's phenomenological treatment of the commensurate and incommensurate phase transitions in the ferroelectric and ferroelastic crystals"Advances in ESR Applications. 15. 1-6 (1999)

Tadashi Kobayashi：“Landau 对铁电和铁弹性晶体中相称和不相称相变的现象学处理”ESR 应用的进展。