Neiuromagnetic study on speech sound processing in human auditory cortex

人类听觉皮层语音处理的神经磁学研究

基本信息

批准号：
03455002
负责人：
KURIKI Shinya
金额：
$ 2.69万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1991
资助国家：
日本
起止时间：
1991 至 1992
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-03455002/
关键词：
Neuromagnetic Field SQUID Auditory Cortex Voice Processing Auditory Evoked Field

项目摘要

We have been studied the neural activities in the human auditory cortex concerning with the speech sound processing by measuring neuromagnetic fields. Obtained results are summarized as follows.1. Background noises in the auditory evoked magnetic field responses recorded with a 37 channel SQUID magnetometer have been studied. The background noise was found to have a main contribution from the spontaneous fields, which originate in the neural activities of the brain. The spontaneous fields had strong spatial correlation across the recording sites even after averaging over 100 epochs. Furthermore, the signal to noise ratio, which is needed for accurate source localization, was determined from the experiments.2. The relationship between tinnitus and auditory neural activities was studied based on the neuromagnetic fields. It was found that either Nlm or Plm component increases due to the suppression of tinnitus by electrical stimulation to cochlea under some circumstances.3. Neuromagnetic fields evoked by monosyllable speech sounds, i.e. /a/, /ka/, /ha/ and /na/, have been measured using a 37 channel SQUID magnetometer. Parameters of a dipole current source have been estimated using several sets of field data recorded in different measurement runs. It was found from the results that statio-temporal movements of the sources depend on the subjects as well as stimuli. However, the sources of N1m components evoked by /a/ and /na/ commonly move either to anterior, medial or posterior direction in all subjects.

通过测量神经磁场，我们已经研究了人类听觉皮层中有关语音处理的神经活动。获得的结果总结如下1。已经研究了使用37通道鱿鱼磁力计记录的听觉磁场响应中的背景噪声。发现背景噪声具有自发场的主要贡献，源自大脑的神经活动。即使在平均100个时代，自发场在整个记录位点之间具有很强的空间相关性。此外，从实验中确定了准确源定位所需的信号与噪声比。2。耳鸣与听觉神经活动之间的关系是根据神经磁场研究的。发现在某些情况下，NLM或PLM成分通过电刺激对耳蜗的电刺激而增加。3。通过37频道鱿鱼磁力计测量了由单音节语音声音引起的神经磁场，即 /a /， /ka /， /ha /and /na / /。偶极电流源的参数已使用不同测量运行中记录的几组字段数据估算。从结果可以发现，来源的统计运动取决于受试者和刺激。但是， / a /和 / na / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / / na /的源通常移至所有受试者的前，内侧或后方向。