Analysis of brain activities and investigation of hierarchical language processing

大脑活动分析和分层语言处理研究

基本信息

批准号：
15300148
负责人：
KURIKI Shinya
金额：
$ 10.05万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15300148/
关键词：
Magnetoencephalography Language Inverse problem Grammar Noninvasive measurement Imaging Syntax processing MEG(脳磁図)

项目摘要

The research is aimed at elucidating spatiotemporal neural activities during sentence reading. To analyze multiple activities within the brain, minimum L1 norm reconstruction was examined by simulation. It was found that the locating accuracy was within about 5 mm when a gravitational center of estimated dipole sources was computed, where the standard error was about 15 mm. The dipole moments, which were estimated for multiple subjects, were averaged by using Gaussian function with the above standard error in standard brain coordinates, which enabled visualization of distributed brain activities.In MEG measurements we used Japanese complex sentences that included a main clause, in a canonical phrase-order of subject (S) - object (O) -verb (V), combined with a subordinate clause. Sentences that had the main clause of scrambled O-S-V phrases were also composed and mixed. Those sentences were presented visually phrase-to-phrase to subjects. They performed a judgment task during MEG record … More ing, answering a question given in canonical-order phrases about the thematic role, i.e., "who did whom what" of the main clause. MEG responses of different phrases in the main clause were averaged, from which distributed current sources were estimated by L1 norm method.Grand mean distribution across eleven subjects of the localized sources showed regional activities focused in the prefrontal and posterior temporal areas in the left hemisphere, which may overlap with classical language areas. Activities were also found around the left central sulcus, indicating sensory/motor cortices, centered at the hand area. These active regions, together with visual occipital cortices were observed in most subjects, though large inter-subject varialbilities existed in the magnitude and extent of the activities. Posterior part of the prefrontal area and the sensory/motor areas were more active for scrambled than canonical sentences. No focal activities in the central and prefrontal regions were observed in the right hemisphere. Less

该研究旨在阐明句子阅读期间的空间时间神经活动。为了分析大脑内的多个活动，通过模拟检查了最小L1规范重建。发现当计算估计偶极子源的重力中心时，定位精度在约5 mm之内，标准误差约为15 mm。 The dipole moments, which were estimated for multiple subjects, were averaged by using Gaussian function with the above standard error in standard brain coordinates, which enabled visualization of distributed brain activities.In MEG measurements we used Japanese complex sentences that included a main clause, in a canonical phrase-order of subject (S) - object (O) -verb (V), combined with a subordinate clause.还组成并混合了炒O-S-V短语的主要子句的句子。这些句子在视觉上向受试者提供了视觉短语。他们在MEG记录中执行了法官任务……更多，回答了有关主题角色的规范订单短语中给出的一个问题，即“谁在主条款中做了什么”。主子句中不同短语的MEG响应平均，通过L1 Norm方法估算了分布式电流源。在局部活动的11个受试者之间的较高平均分布，显示了集中在左半球前和后临时区域的区域活动，左半球可能与经典语言重叠。还发现了左中央沟周围的活动，表明以手动区域为中心的感觉/运动皮层。在大多数受试者中观察到这些活性区域以及视觉枕皮层，尽管在活动的大小和程度中存在大型受试者间的静脉曲张。前额叶区域的后部和感觉/运动区域比规范句子更活跃。在右半球中未观察到中央和前额叶区域的焦点活性。较少的

项目成果

期刊论文数量（39）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

S.Kuriki, T.Mishima, F.Takeuchi, H.Hagiwara, J.Arigi: "MEG study of brain areas involved in syntactic processing of Japanese complex sentences"Abstract of IBRO World Congress of Neuroscience (Prague). 6. 3387 (2003)

S.Kuriki、T.Mishima、F.Takeuchi、H.Hagiwara、J.Arigi：“参与日语复杂句子句法处理的大脑区域的 MEG 研究”IBRO 世界神经科学大会（布拉格）摘要。

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0
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文処理の脳内メカニズム

句子处理的大脑机制

DOI：
发表时间：
2003
期刊：
Clinical Neuroscience 21・7
影响因子：
0
作者：
KUBO;Fumiaki;萩原裕子
通讯作者：
萩原裕子

萩原裕子: "文処理の脳内メカニズム"Clinical Neuroscience. 21・7. 783-786 (2003)

萩原裕子：“句子处理的大脑机制”《临床神经科学》21・786（2003）。

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0
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萩原裕子, 曽雌崇弘: "かき混ぜ文の処理について-多チャンネル脳波による検討-"意図の伝達スキルに関する国際シンポジウム開催準備研究公開シンポジウム論文集. 35-44 (2003)

Yuko Hagiwara，Takahiro Some：“关于混合句子的处理-使用多通道脑电波的研究”国际意图沟通技巧研讨会筹备研究公共研讨会论文集35-44（2003）。

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0
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Auditory evoked field responses in the left hemisphere to morphosyntactic violation in Korean sentence

韩语句子中，听觉诱发左半球对形态句法违规的反应

DOI：
发表时间：
2004
期刊：
Biomag 2004 Proceedings of the 14th International Conference on Biomagnetism, Boston
影响因子：
0
作者：
H.Kwon;J.Kim;Y.Lee;K.Kim;Y.Park;K.Nam;S.Kuriki
通讯作者：
S.Kuriki