Priming of plant defence against pathogens and herbivores by DNA damage signalling (B05)

通过 DNA 损伤信号启动植物防御病原体和食草动物 (B05)

• 批准号: 358447592
• 金额: --
• 依托单位: Abteilung Biochemie pflanzlicher Interaktionen
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/358447592?language=en
• 关键词: Priming; plant; defence; against; pathogens

Phytopathogen infections lead to plant DNA damage; several components of DNA damage responses are required for activation of plant innate immunity. Application of bleomycin, a DNA double strand break-inducing glycopeptide, can prime the expression of plant defence genes against subsequent pathogen stress over several days. Project B5 will study molecular mechanisms underlying this priming effect. Insect oviposition on leaves leads to transcriptome changes that resemble those upon pathogen attack. Therefore, we will also assess if oviposition elicits DNA lesions and whether molecular responses to DNA damage contribute to oviposition-mediated anti-herbivore priming.

植物病原体感染导致植物 DNA 损伤；激活植物先天免疫需要 DNA 损伤反应的几个组成部分。博来霉素（一种 DNA 双链断裂诱导糖肽）的应用可以在几天内启动植物防御基因的表达，以抵抗随后的病原体胁迫。 B5 项目将研究这种启动效应的分子机制。昆虫在叶子上产卵会导致转录组变化，类似于病原体攻击时的变化。因此，我们还将评估产卵是否引起 DNA 损伤，以及对 DNA 损伤的分子反应是否有助于产卵介导的反草食动物启动。