Scripps Center for Oceans and Human Health: advancing the science of marine contaminants and seafood security

斯克里普斯海洋与人类健康中心：推进海洋污染物和海鲜安全的科学

• 批准号: 2414798
• 负责人: Bradley Moore
• 金额: $ 432.3万
• 依托单位: University of California-San Diego Scripps Inst of Oceanography
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-01 至 2029-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2414798&HistoricalAwards=false
• 关键词: Scripps; Center; Oceans; Human; Health

The Scripps Center for Oceans and Human Health (SCOHH) is a five-year effort to advance the science and community engagement surrounding seafood pollutants, on a rapidly changing planet. The project brings together a multidisciplinary team of biomedical and oceanographic researchers with expertise in fish ecology, microbiology, marine chemistry, climate modeling, technology development, bioaccumulation, genomics, toxicology, and public health. The Center’s scientific goals and focus are guided by the needs of society, established through bidirectional community engagement, and led by a proven community engagement team. The proposed research program of SCOHH spans four main areas:1. Climate change impacts on the human intake of seafood micronutrients and contaminants. 2. The marine microbiome as a source for the synthesis, transformation, and distribution of seafood contaminants. 3. Mechanisms of bioaccumulation and developmental toxicity of seafood pollutants. 4. Bidirectional public engagement and literacy surrounding seafood risks and benefits.The outcomes of the SCOHH will inform policies, consumption guidelines, and individual decisions to lower risk and enhance greater benefits associated with seafood consumption. Internally, SCOHH will take deliberate measures to enhance equity, diversity, and inclusion in all aspects of its functioning, from the investigator team and graduate student/postdoctoral trainees to engagement with community partners. The Center is jointly supported by NSF’s Division of Ocean Sciences and by the National Institute for Environmental Health Sciences (NIEHS).The central scientific theme of SCOHH is to advance knowledge of marine contaminants and seafood security. Natural and anthropogenic contaminants such as mercury, DDT, and PCBs drive seafood consumption advisories. Yet understanding of their sources, microbial transformations, toxicity, and potential for climate driven change remain incomplete. The SCOHH team will study and track the distribution of essential micronutrients and harmful contaminants in marine food webs to the three billion people who consume seafood globally, the roles that the marine microbiome play in their production and transport, and the developmental toxicity of seafood pollutants and their interactions with transporters that determine uptake and bioaccumulation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

斯克里普斯海洋与人类健康中心 (SCOHH) 是一个为期五年的项目，旨在在快速变化的星球上推动围绕海鲜污染物的科学和社区参与，该项目汇集了一支由具有鱼类专业知识的生物医学和海洋学研究人员组成的多学科团队。该中心的科学目标和重点以社会需求为指导，通过双向社区参与建立，并由社区领导。 SCOHH 拟议的研究计划涵盖四个主要领域：1. 气候变化对人类摄入海鲜微量营养素和污染物的影响。 3. 海鲜污染物的生物累积和发育毒性机制 4. 公众对海鲜风险和益处的双向参与和认识。SCOHH 的结果将为政策、消费指南和个人决策提供信息。为了降低与海鲜消费相关的风险并提高更大的收益，SCOHH 将采取审慎措施，以增强其运作各个方面的公平性、多样性和包容性，从研究团队和研究生/博士后学员到社区合作伙伴的参与。该中心由 NSF 海洋科学部和国家环境健康科学研究所 (NIEHS) 共同支持。SCOHH 的中心科学主题是增进对海洋污染物和海产品安全的了解，例如天然和人为污染物。然而，对于汞、滴滴涕和多氯联苯的来源、微生物转化、毒性和气候驱动变化的潜力的了解仍然不完整，SCOHH 团队将研究和跟踪海洋食物网中必需微量营养素和有害污染物的分布。向全球 30 亿消费海鲜的人介绍海洋微生物群在其生产和运输中所发挥的作用，以及海鲜污染物的发育毒性及其与决定吸收和运输的转运蛋白的相互作用。这反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。