I-Corps: Catalytic Porous Organic Polymers

I-Corps：催化多孔有机聚合物

• 批准号: 2324992
• 负责人: Timothy Swager
• 金额: $ 5万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2324992&HistoricalAwards=false
• 关键词: Corps; Catalytic; Porous; Organic; Polymers

The broader impact/commercial potential of this I-Corps project is the development of catalytic materials that will enable the more efficient and green production of high value materials including pharmaceuticals and dyes. These proposed catalysts may be recycled or used for extended periods and are easily separated from the final products, which simplifies the manufacturing of these materials. In addition, the proposed materials materials have an advantage by making use of porous organic polymers that may provide solution-like reactivities as well as the advantages of a supported surface immobilized catalyst. The recyclable and ease of separation combine to create systems that may be used in conventional or emerging production methods and lower production costs. This I-Corps project is based on the development of new concepts in catalysis enabled by new generations of polymers with high degrees of internal free volume. These proposed polymers have high degrees of porosity and are created by molecular level designs that fuse non-compliant 3D monomers directly into the polymer backbone. The polymer structures are modular and can include structures capable of reactions that are promoted by light that oxidize of reduce compounds (photoredox reactivity), as well as thermochemical metal catalyzed reactions. Catalytic polymers can be bound to magnetic inorganic magnetic particles, glass sidewalls of reactors, on stirring turbines, or on the surfaces of tubing. The polymer structures and pockets around the catalytic sites can produce selectivity and high numbers of turnovers. In the case of photoredox catalytic materials, the polymers display much higher rates than molecular catalysts dissolved in solution, as a result of their excitonic and charge transporting abilities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该I-Corps项目的更广泛的影响/商业潜力是开发催化材料，这些材料将使包括药品和染料在内的高价值材料的效率更高和绿色产生。 这些提出的催化剂可以延长或长时间使用，并且很容易与最终产品分离，从而简化了这些材料的生产。此外，提出的材料通过利用可提供溶液样反应性的多孔有机聚合物以及受支持的表面固定化催化剂的优势而具有优势。 可回收和易于分离的结合在一起，可以创建可能用于常规或新兴生产方法和降低生产成本的系统。这个I-Corps项目基于具有高度内部自由体积的新一代聚合物启用的新概念的发展。 这些提出的聚合物具有较高的孔隙率，并且是由分子水平设计产生的，这些设计将不合格的3D单体直接融合到聚合物主链中。 聚合物结构是模块化的，可以包含能够通过氧化减少化合物（Photoredox反应性）以及热化学金属催化反应而促进反应的结构。 催化聚合物可以与磁性无机磁性颗粒，反应器的玻璃侧壁，搅拌涡轮机或管道表面结合。 催化位点周围的聚合物结构和口袋可以产生选择性和大量失误。 对于光毒素催化材料，由于其激素和电荷运输能力，聚合物的速率比溶解在溶液中的分子催化剂的速率要高得多。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的评估来通过评估来支持的。智力优点和更广泛的影响审查标准。