Acquisition of Helium Recovery Equipment: Orbitrap Fourier Transform Isotope Ratio Mass Spectrometer for Environmental and Climate Research.

购置氦回收设备：Orbitrap 傅里叶变换同位素比质谱仪，用于环境和气候研究。

• 批准号: 2318987
• 负责人: Becky Alexander
• 金额: $ 123.64万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2318987&HistoricalAwards=false
• 关键词: Acquisition; Helium; Recovery; Equipment; Orbitrap

The specific aim of this project is to acquire an Orbitrap Isotope Ratio Mass Spectrometer (IRMS) at the University of Washington (UW) which houses a multi-user laboratory facility specializing in stable isotope ratio measurements. The university laboratory currently contains five gas-source IRMSs that measure hydrogen, oxygen, carbon, sulfur, and nitrogen isotope ratios from a variety of chemical species after conversion of those species to a low molecular weight gas. Current applications of stable isotope measurements are highly varied and include temperature reconstruction from ice cores and sediment cores, proxies for paleo atmospheric oxidant abundance from ice cores, endangered orca food web reconstruction, provenance of illicitly trafficked pangolin scales, and elucidating the co-evolution of life and oxygen in the atmosphere. New developments in Orbitrap mass spectrometry, however, have made this instrument sensitive enough for isotope ratio measurements of intact molecules with no need to convert them to a low molecular weight gas before isotopic measurement.The researchers will use the Orbitrap IRMS to test several specific scientific hypotheses on the topics of paleo atmospheric chemistry, co-evolution of oxygen and life in the mid-Archean, and the specific mechanism of carbon-carbon bond forming processes within metabolites. All three of these projects cannot be achieved with traditional gas-source isotope ratio mass spectrometers due to their mass resolving limitations and the need to convert species to a low molecular weight gas. Given that Orbitrap IRMS is an emerging technology, expansion of its utility and scientific application is planned beyond the initial research projects for which Orbitrap IRMS may transform what can be potentially learned from isotope ratio measurements in a variety of fields and enable researchers to answer more complicated scientific questions.The potential Broader Impacts are mainly focused on the scientific applications of the new instrumentation across a wide array of scientific undertakings across six departments and three colleges. Even so, several undergraduate and graduate students will be trained in cutting edge Orbitrap IRMS technology thereby enhancing their professional opportunities. Furthermore, this instrumentation will enhance the University of Washington’s active participation in programs promoting opportunities in education and research (UW ADVANCE Program, the Pacific Northwest Louis Strokes Alliance for Minority Participation) and its connection with K-12 students and faculty in Seattle schools and rural and tribal communities across the state.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该项目的具体目的是购买华盛顿大学（UW）的Orbitrap同位素比率质谱仪（IRMS），该大学拥有多用户实验室设施，专门研究稳定的同位素比测量值。该大学实验室目前包含五个气体源IRMS，这些IRMS测量了这些物种转化为低分子量气体后的各种化学物质的氢，氧，碳，硫和氮同位素比。稳定同位素测量的当前应用高度多样，包括冰块和沉积物核心的温度重建，冰核的古大气氧化丰度的代理，濒临灭绝的ORCA食物网络重建，危险的offention offention，危险的食物网络重建，非法贩运的佩顿奶油素尺度以及阐明了生命和氧气中氧化物的共同流入。 New developments in Orbitrap mass spectrometry, however, have made this instrument sensitive enough for isotope ratio measurements of intact molecules with no need to convert them to a low molecular weight gas before isotopic measurement.The researchers will use the Orbitrap IRMS to test several specific scientific hypotheses on the topics of paleo atmospheric chemistry, co-evolution of oxygen and life in the mid-Archen, and the specific mechanism代谢产物内的碳碳键形成过程。由于传统的气体源比率质谱仪无法实现这三个项目，因为它们的质量解决局限性以及将物种转换为低分子量气体的需求。鉴于Orbitrap IRMS是一项新兴技术，因此计划扩展其实用性和科学应用，而不是最初的研究项目，该项目可能会改变各种领域的同位素比率测量可能从同位素比率中学到的知识，并使研究人员能够回答更为复杂的科学影响，从而在科学方面进行了更为复杂的科学影响，从而跨越了科学范围。大学。即便如此，一些本科生和研究生将接受尖端Orbitrap IRMS技术的培训，从而增强他们的职业机会。 Furthermore, this instrumentation will enhance the University of Washington’s active participation in programs promoting opportunities in education and research (UW ADVANCE Program, the Pacific Northwest Louis Strokes Alliance for Minority Participation) and its connection with K-12 students and faculty in Seattle schools and rough and tribal communities across the state.This award reflects NSF's statutory mission and has been deemed precious of support through evaluation using the Foundation's intellectual merit and broader影响审查标准。