MRI: Acquisition of a Dual-Source Single-Crystal X-ray Diffractometer.

MRI：购买双源单晶 X 射线衍射仪。

• 批准号: 2214606
• 负责人: Allen Oliver
• 金额: $ 28.7万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2025-08-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2214606&HistoricalAwards=false
• 关键词: MRI; Acquisition; Dual; Source; Single

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. The University of Notre Dame is acquiring a dual-source single crystal diffractometer equipped with high-flux Cu and Mo microfocus X-ray sources, a CPAD detector, and a cryogenic device to support the research of Professor Allen Oliver and colleagues Vlad Iluc, and Emily Tsui. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of undergraduate and graduate students in chemistry and biochemistry at this institution. The facility serves as a regional XRD resource benefitting students and faculty from primarily undergraduate institutions within the state of Indiana with impacts outside ND through active collaborations with researchers at institutions such as Tennessee Tech University, St. Mary’s College, Elizabethtown College, and the University of Victoria, B.C., and maintains private sector affiliations. They have developed international collaborations with colleagues from Chile, Canada, and New Zealand.The award is aimed at enhancing research and education at all levels. Research enabled by the instrument is focused on the study and characterization of a wide variety of substances including enantiopure and chiral organic compounds, drug precursors and other biologically important molecules, organometallic and inorganic complexes and mineral-like materials. Structure determination of metal complexes (e.g., catalysis), solid-state materials (e.g., energy conversion), and absolute configurations of light-atom molecules (e.g., natural products) is essential to drive research in these fields.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器和化学研究仪器计划联合资助，圣母大学正在购买一台双源单晶衍射仪，配备高通量铜和钼微焦点 X 射线源、CPAD 探测器和支持 Allen Oliver 教授及其同事 Vlad Iluc 和 Emily Tsui 的研究的低温装置 一般来说，X 射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于相邻分子的空间排列的准确信息。这里描述的研究影响许多领域，包括有机和无机化学、材料化学和生物化学。该机构作为区域 XRD 资源，通过与印第安纳州研究人员的积极合作，使印第安纳州内主要本科院校的学生和教师受益，并在 ND 以外产生影响。机构如田纳西理工大学、圣玛丽学院、伊丽莎白敦学院和不列颠哥伦比亚省维多利亚大学，并与来自智利、加拿大和新西兰的同事建立了国际合作关系。该奖项旨在加强研究和发展。该仪器支持的研究重点是各种物质的研究和表征，包括对映体纯和手性有机化合物、药物前体和其他重要的生物学分子、有机金属和无机复合物以及类矿物。金属配合物（例如催化）、固态材料（例如能量转换）和轻原子分子（例如天然产物）的绝对构型的结构测定对于推动这些领域的研究至关重要。该奖项反映了通过使用基金会的智力价值和更广泛的影响审查标准进行评估，NSF 的法定使命被认为值得支持。