GRC/GRS Venom Evolution, Function and Biomedical Applications: Bridging Gaps in Venom Research: From Ecology and Evolution to Socio-Economic Impacts

GRC/GRS 毒液进化、功能和生物医学应用：弥合毒液研究的差距：从生态学和进化到社会经济影响

• 批准号: 2221307
• 负责人: Micaiah Ward
• 金额: $ 2.02万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-01 至 2022-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2221307&HistoricalAwards=false
• 关键词: GRC; GRS; Venom; Evolution; Function

The Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Venom Evolution, Function and Biomedical Applications represent unique international forums to share cutting-edge research on the evolution, function, and applications of venom. Animal venoms are key evolutionary adaptations that have originated independently in many animal lineages to assist in defense, predation, and competition. Venoms are some of the most complex secretions known in nature and are made up of toxins and other bioactive compounds whose molecular structure and targets are often similar throughout the animal kingdom. These features make venoms excellent systems to answer fundamental questions in evolutionary biology, and these toxins are untapped resources of novel compounds with great potential for biotechnological applications including drug leads and pesticides. The Venom GRC and GRS will bring together senior and junior researchers from academia and industry to define key areas of venom research, establish collaborations to advance the field, and evaluate challenges and opportunities to achieve a greater impact in basic and applied science. This award will specifically enable early career researchers, including graduate students, postdocs, women and other underrepresented minorities in science, to attend both the 2022 Venom GRS (August 6-7, 2022) and GRC (August 7-12, 2022). This will provide an excellent platform for early career researchers to share their work, while establishing connections and international networks leading to collaborations that will advance venom research. The GRS specifically will aid in this endeavor by concluding with a panel of mentors from industry and academia to offer career advice and discuss their background with attendees, fostering the careers of the future leaders of venom research. The specific theme of the 2022 Venom GRC and GRS is “Bridging Gaps in Venom Research: From Ecology and Evolution to Socio-Economic Impacts”. The combined programs include 13 topical sessions featuring invited speakers and selected presentations by both early career and established researchers, and six interactive poster sessions to provide participants with a world-class view of the interdisciplinarity of venom research. The sessions highlight some of the most important challenges and opportunities for collaboration and interdisciplinary innovation in the venom field and include “Functional Ecology and Biodiversity of Venom”, “Emerging Models in Venom Research”, “Toxin Structure and Function” and “Biomedical and Pesticidal Applications of Venom” among others. The guiding principle of GRC and GRS is to encourage communication, discussion of ideas and unpublished results at the frontier of the field, emphasizing personal interactions and community-building. As such, these GRC and GRS meetings are an outstanding opportunity to build a strong, diverse and cohesive venom research community able to cultivate innovative approaches to address the most important challenges and opportunities for the field of venom research.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

关于毒液进化，功能和生物医学应用的戈登研究会议（GRC）和戈登研究研讨会（GRS）代表了有关毒液的进化，功能和应用的独特国际论坛。动物毒液是主要起源于许多动物谱系的关键进化适应，以帮助防御，准备和竞争。毒液是自然界已知的一些最复杂的分泌物，是由毒素和其他生物活性化合物组成的，其分子结构和靶标在整个动物界通常相似。这些功能使毒液使得毒液在进化生物学中回答基本问题，这些毒素是未开发的新型化合物资源，具有巨大潜力，用于生物技术应用，包括药物铅和农药。 Venom GRC和GRS将汇集来自学术界和行业的高级和初级研究人员，以定义毒液研究的关键领域，建立合作以推进该领域，并评估挑战和机会，以对基本和应用科学产生更大的影响。该奖项将特别使早期的职业研究人员，包括研究生，博士后，妇女和其他代表性不足的科学少数群体，都可以参加2022 Venom GRS（8月6日至7日，2022年8月6日至7日）和GRC（2022年8月7日至12日）。这将为早期职业研究人员分享他们的工作提供一个绝佳的平台，同时建立联系和国际网络，从而实现可以推进毒液研究的合作。 GRS将通过与行业和学术界的一组导师小组结束，以提供职业建议和讨论与与会者的背景，从而促进了毒液研究的未来领导者的职业。 2022年毒液GRC和GRS的具体主题是“毒液研究中的弥合差距：从生态和进化到社会经济影响”。合并后的计划包括13次拓扑会议，包括邀请演讲者和早期职业和既定研究人员的精选演讲，以及6次互动海报会议，以使参与者对毒液研究的跨学科性看法。会议突出了一些最重要的挑战和机遇，在毒液领域进行了协作和跨学科创新，包括“功能生态学和毒液的生物多样性”，“毒素研究中的新兴模型”，“毒素结构和功能”，“生物医学和毒液的生物医学和毒素应用”等。 GRC和GRS的指导原则是鼓励该领域边界的沟通，讨论思想和未发表的结果，强调个人互动和社区建设。因此，这些GRC和GRS会议是建立一个强大，潜水和凝聚力的毒液研究社区，能够培养创新的方法来应对毒液研究领域的最重要挑战和机遇。该奖项反映了NSF的法定任务，并通过评估该基金会的知识分子功能和广泛的影响来反映NSF的法定任务，并被视为珍贵的支持。