Conference: 2024 Thiol-Based Redox Regulation and Signaling GRC and GRS: Mechanisms and Consequences of Redox Signaling

会议：2024年基于硫醇的氧化还原调节和信号传导GRC和GRS：氧化还原信号传导的机制和后果

• 批准号: 2418618
• 负责人: Carolyn Sevier
• 金额: $ 1.5万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2418618&HistoricalAwards=false
• 关键词: Conference; 2024; Thiol; Based; Redox

This award supports the 9th biennial Gordon Research Conference (GRC) and the associated Gordon Research Seminar (GRS) on Thiol-Based Redox Regulation and Signaling to be held July 13-19, 2024, at the Rey Don Jaime Grand Hotel in Castelldefels, Spain. This GRC/GRS brings together a diverse international community of chemical biologists, biochemists, cell biologists, and physiologists for a multi-day intensive meeting to present and discuss the latest research in the field, outline the future directions of that work, and establish collaborative relationships to accomplish this future research. The focused, intimate conference format will offer ample opportunities for attendees to engage in in-depth research discussions and facilitate networking. Funds from this award are strictly applied to defray registration costs for U.S.-based graduate students and postdoctoral trainees, to facilitate attendance of a diverse groups of participants from early stages of their careers. A unique professional development opportunity for junior scientists is provided by the GRS. This pre-GRC component of the Conference experience is organized by and for graduate students and postdoctoral fellows, enabling conference planning experience and programming focused on integrating junior scientists into the redox signaling community, promoting the engagement and mentoring of the next generation of scientists, and ensuring the continued vitality of this research field. GRC attendees abide by a strict off-the-record policy to encourage open communication and collaboration, creating a distinctive intellectual experience.The theme of the 2024 GRC is the mechanisms of thiol-based redox signaling, with an emphasis on the spatial and temporal aspects of signaling within and between cells that control life and death decisions. Major meeting topics include tools and technologies for redox biology, signaling via low molecular weight thiols and post-translational modifications, redox control of protein biogenesis and turnover, reactive sulfur species and protein-redox switches, lipid oxidation and redox-dependent cell death, inter-organelle and inter-cellular redox crosstalk, host-pathogen and immune responses, and redox-signaling in metabolism and age-associated pathologies. This GRC/GRS will integrate research, education, training, and career development by strongly encouraging the active participation of a diverse group of junior scientists (graduate students, postdoctoral fellows, and newly appointed faculty) in all aspects of the conference. In addition to formal talks, the conferences include designated time for poster sessions from individuals of all career stages. Poster previews during the morning plenary GRC sessions, a career development panel during the GRS, and a PowerHour event during the GRC, will further support the professional growth of all members of our community. The success of the meeting will be assessed using established GRC guidelines.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项支持第9届双年展戈登研究会议（GRC）和相关的戈登研究研讨会（GRS），该研讨会（GRS）在2024年7月13日至19日在西班牙卡斯特尔德尔的雷伊·唐·贾梅·格兰德酒店（Rey Don Jaime Grand Hotel）举行。这个GRC/GRS汇集了一个多元化的化学生物学家，生物化学家，细胞生物学家和生理学家的多样化国际社会，参加了多天密集会议，以介绍和讨论该领域的最新研究，概述了该工作的未来方向，并建立了协作关系以完成这项未来的研究。专注的，亲密的会议格式将为与会者提供充足的机会进行深入的研究讨论并促进网络。该奖项的资金严格用于支付基于美国的研究生和博士后学员的注册费用，以促进从职业早期阶段的各种参与者的参加。 GRS为初级科学家提供了独特的专业发展机会。会议经验的GRC前组成部分是由研究生和博士后研究员组织的，使会议计划经验和编程专注于将初级科学家整合到氧化还原信号界，促进下一代科学家的参与和指导，并确保该研究领域的持续活力。 GRC的参与者遵守严格的录音政策，以鼓励开放的沟通和协作，创造独特的智力体验。2024 GRC的主题是基于硫醇的氧化还原信号的机制，重点是控制生命和死亡决策的细胞内部和之间信号的空间和时间方面。 Major meeting topics include tools and technologies for redox biology, signaling via low molecular weight thiols and post-translational modifications, redox control of protein biogenesis and turnover, reactive sulfur species and protein-redox switches, lipid oxidation and redox-dependent cell death, inter-organelle and inter-cellular redox crosstalk, host-pathogen and immune responses, and redox-signaling in代谢和与年龄相关的病理。这种GRC/GRS将通过强烈鼓励一群初级科学家（研究生，博士后研究员和新任命的教职员工）的积极参与来整合研究，教育，培训和职业发展。除了正式的会谈外，这些会议还包括所有职业阶段个人的海报会议的指定时间。海报预览在早晨全体GRC会议上，GRS期间的职业发展小组以及GRC期间的PowerHour活动，将进一步支持我们社区所有成员的专业成长。会议的成功将使用既定的GRC指南进行评估。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛的影响评估标准来评估的。