Conference: 2024 Thiol-Based Redox Regulation and Signaling GRC and GRS: Mechanisms and Consequences of Redox Signaling

会议：2024年基于硫醇的氧化还原调节和信号传导GRC和GRS：氧化还原信号传导的机制和后果

• 批准号: 2418618
• 负责人: Carolyn Sevier
• 金额: $ 1.5万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2418618&HistoricalAwards=false
• 关键词: Conference; 2024; Thiol; Based; Redox

This award supports the 9th biennial Gordon Research Conference (GRC) and the associated Gordon Research Seminar (GRS) on Thiol-Based Redox Regulation and Signaling to be held July 13-19, 2024, at the Rey Don Jaime Grand Hotel in Castelldefels, Spain. This GRC/GRS brings together a diverse international community of chemical biologists, biochemists, cell biologists, and physiologists for a multi-day intensive meeting to present and discuss the latest research in the field, outline the future directions of that work, and establish collaborative relationships to accomplish this future research. The focused, intimate conference format will offer ample opportunities for attendees to engage in in-depth research discussions and facilitate networking. Funds from this award are strictly applied to defray registration costs for U.S.-based graduate students and postdoctoral trainees, to facilitate attendance of a diverse groups of participants from early stages of their careers. A unique professional development opportunity for junior scientists is provided by the GRS. This pre-GRC component of the Conference experience is organized by and for graduate students and postdoctoral fellows, enabling conference planning experience and programming focused on integrating junior scientists into the redox signaling community, promoting the engagement and mentoring of the next generation of scientists, and ensuring the continued vitality of this research field. GRC attendees abide by a strict off-the-record policy to encourage open communication and collaboration, creating a distinctive intellectual experience.The theme of the 2024 GRC is the mechanisms of thiol-based redox signaling, with an emphasis on the spatial and temporal aspects of signaling within and between cells that control life and death decisions. Major meeting topics include tools and technologies for redox biology, signaling via low molecular weight thiols and post-translational modifications, redox control of protein biogenesis and turnover, reactive sulfur species and protein-redox switches, lipid oxidation and redox-dependent cell death, inter-organelle and inter-cellular redox crosstalk, host-pathogen and immune responses, and redox-signaling in metabolism and age-associated pathologies. This GRC/GRS will integrate research, education, training, and career development by strongly encouraging the active participation of a diverse group of junior scientists (graduate students, postdoctoral fellows, and newly appointed faculty) in all aspects of the conference. In addition to formal talks, the conferences include designated time for poster sessions from individuals of all career stages. Poster previews during the morning plenary GRC sessions, a career development panel during the GRS, and a PowerHour event during the GRC, will further support the professional growth of all members of our community. The success of the meeting will be assessed using established GRC guidelines.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项支持将于 2024 年 7 月 13 日至 19 日在西班牙卡斯特尔德费尔斯 Rey Don Jaime 大酒店举行的第九届两年一度的戈登研究会议 (GRC) 以及相关的关于基于硫醇的氧化还原调节和信号传导的戈登研究研讨会 (GRS) 。此次 GRC/GRS 汇集了化学生物学家、生物化学家、细胞生物学家和生理学家等多元化国际团体，召开为期多天的密集会议，介绍和讨论该领域的最新研究，概述该工作的未来方向，并建立合作关系关系来完成这项未来的研究。重点突出、亲密的会议形式将为与会者提供充足的机会进行深入的研究讨论并促进交流。该奖项的资金严格用于支付美国研究生和博士后实习生的注册费用，以促进不同群体的参与者从职业生涯的早期阶段就可以参加。 GRS 为初级科学家提供了独特的专业发展机会。会议经验的 GRC 前部分由研究生和博士后研究员组织，旨在提供会议规划经验和计划，重点是将初级科学家融入氧化还原信号社区，促进下一代科学家的参与和指导，以及保证了该研究领域的持续活力。 GRC与会者遵守严格的非正式政策，鼓励开放交流与合作，创造独特的智力体验。2024年GRC的主题是基于硫醇的氧化还原信号传导机制，重点关注空间和时间方面控制生死决定的细胞内部和细胞之间的信号传导。主要会议主题包括氧化还原生物学的工具和技术、通过低分子量硫醇和翻译后修饰传递信号、蛋白质生物发生和周转的氧化还原控制、活性硫物质和蛋白质氧化还原开关、脂质氧化和氧化还原依赖性细胞死亡等-细胞器和细胞间氧化还原串扰、宿主病原体和免疫反应，以及代谢和年龄相关病理中的氧化还原信号传导。 GRC/GRS 将通过大力鼓励多元化的青年科学家（研究生、博士后研究员和新任命的教员）积极参与会议的各个方面，将研究、教育、培训和职业发展融为一体。除了正式会谈之外，会议还包括指定时间为各个职业阶段的个人举办海报会议。 GRC 上午全体会议期间的海报预览、GRS 期间的职业发展小组以及 GRC 期间的 PowerHour 活动将进一步支持我们社区所有成员的专业成长。会议的成功与否将使用既定的 GRC 指南进行评估。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。