Conference: 2024 Microbial Stress Response GRC and GRS: Dealing with the Unknown: Bacterial Stress Responses Across Time and Space

会议：2024年微生物应激反应GRC和GRS：应对未知：跨时间和空间的细菌应激反应

• 批准号: 2420525
• 负责人: Amy Schmid
• 金额: $ 1.5万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-15 至 2025-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2420525&HistoricalAwards=false
• 关键词: Conference; 2024; Microbial; Stress; Response

This award supports the 2024 Gordon Research Seminar and Conference on “Microbial Stress Response,” held July 14-19th at Mount Holyoke College in Massachusetts. This meeting brings together a demographically diverse group of 200 international scientists seeking to understand how microbes sense and respond to challenging and ever-changing environments. Understanding how microbes respond to stress has wide-reaching impacts on areas such as biotechnology, ecology, and environmental biology, as well as the symbiosis and pathogenesis relationships that microbes establish with the hosts they infect. In addition to formal talks presented by experienced researchers and trainees new to the field, engagement is facilitated by poster presentations to stimulate one-on-one interactions between researchers. NSF support defrays travel costs to allow attendance of diverse participants from early stages of their careers. This meeting therefore provides critical training opportunities for the next generation of scientists.Bacteria and Archaea face a nearly constant onslaught of diverse stressors, including nutrient limitations, temperature changes, antibiotics, phage, host immune systems, and more. Whether they can properly detect and respond to such stressors largely determines their survival in a world of fierce competition. Microbes have evolved finely tuned and sophisticated regulatory mechanisms for responding to stress by controlling genome duplication and repair, gene expression, proteostasis, RNA processing, and both central and secondary metabolism. Collectively, these responses enable survival in a range of harsh conditions. Thus, delineating how microbes respond to stress will elucidate the fundamental principles governing key cellular processes that are conserved from bacteria to humans. The meeting brings together seasoned investigators with early-career scientists through both formal talks and discussion sessions to encourage informal sharing on areas such as new approaches to understanding interactions between microbes and the environment, particularly modern imaging, genetic, metagenomic, and computational strategies for the analysis of bacterial physiology and community structures under conditions of stress and competition.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项支持2024年戈登研究研讨会和关于“微生物压力反应”的会议，于7月14日至19日在马萨诸塞州的霍利奥克山学院举行。这次会议汇集了一个人口统计学多元化的200个国际科学家，他们试图了解微生物如何对挑战和不断变化的环境做出回应。了解微生物对压力的反应如何对生物技术，生态学和环境生物学等领域以及微生物与他们感染的宿主建立的共生和发病机理关系产生广泛的影响。除了经验丰富的研究人员和培训该领域的培训的正式谈判外，参与者还得到了海报演示，以刺激研究人员之间的一对一互动。 NSF支持拨款成本，以允许从职业的早期阶段参加潜水员参与者。因此，这次会议为下一代科学家提供了关键的培训机会。细菌和古细菌几乎面临着潜水员压力源的猛烈攻击，包括营养限制，温度变化，抗生素，噬菌体，托管免疫系统等。他们是否可以正确检测并对这种压力源做出反应，在很大程度上决定了他们在激烈竞争的世界中的生存。微生物通过控制基因组重复和修复，基因表达，蛋白质量，RNA加工以及中央和次级代谢，通过控制基因组重复和修复，基因表达，蛋白质症，蛋白质症，基因表达，基因表达，蛋白质和次要代谢来响应压力。总的来说，这些反应能够在一系列危险条件下生存。这就是描述微生物如何应对压力的方式将阐明从细菌到人类保守的关键细胞过程的基本原理。这次会议通过正式的谈判和讨论会议将经验丰富的调查人员与早期的研究人员聚集在一起，以鼓励在诸如了解微生物与环境之间的互动的新方法上进行非正式共享，尤其是现代成像，遗传，遗传学，宏基因组和计算策略，以及在压力和竞争中的分析，以评估奖励的条件。基金会的智力优点和更广泛的影响评论标准。