PFI-TT: Developing a Device to Improve Lymphatic Flow

PFI-TT：开发一种改善淋巴流动的装置

• 批准号: 2213912
• 负责人: Linda Koehler
• 金额: $ 25万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2213912&HistoricalAwards=false
• 关键词: PFI; TT; Developing; Device; Improve

The broader impact/commercial potential of this Partnerships for Innovation - Technology Translation (PFI-TT) project will be in developing a wearable medical device as a new solution for patients with lymphedema, a condition in which fluid build up causes swelling, especially in the arms or legs. The device will improve the body fluid circulation while significantly reducing the risk of severe complications associated with this disease. The goal is to address health disparities and to improve the overall health outcomes of patients suffering from lymphedema. The proposed project focuses on developing an emerging medical technology to address lymphedema, which is a major public health issue in the United States. Lymphedema is characterized by chronic swelling of a body part which has debilitating effects and negatively impacts the quality of life of the patient. A compact, wearable, and simple to operate medical device will be built that will apply therapeutic pressure gradients with the goal of improving lymphatic flow. This technology may significantly enhance current therapeutic modalities when compared to compressive methods that use pneumatic pressure to squeeze out lymph fluid. The proposed technology will have two key mechanical elements: the patch and the controller, designed in a way to mimic the manual lymph drainage techniques. The technology may enhance current therapeutic clinical modalities and be extended to home-based therapies.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这种创新合作伙伴关系的更广泛的影响/商业潜力 - 技术翻译（PFI -TT）项目将在开发可穿戴医疗设备作为淋巴水肿的患者的新解决方案中，在这种情况下，流体会导致肿胀，尤其是在这种情况下，尤其手臂或腿。 该设备将改善体液循环，同时显着降低与该疾病有关的严重并发症的风险。目的是解决健康差异，并改善患有淋巴肿患者的整体健康状况。拟议的项目着重于开发新兴的医疗技术来解决淋巴水肿，这是美国的主要公共卫生问题。淋巴水肿的特征是身体部位的慢性肿胀，其具有令人衰弱的作用，并对患者的生活质量产生负面影响。将建立一个紧凑，可穿戴且易于操作的医疗设备，该设备将应用治疗压力梯度，以改善淋巴流量。 与使用气动压力挤压淋巴液的压缩方法相比，该技术可能会显着增强当前的治疗方法。 所提出的技术将具有两个关键的机械元素：贴片和控制器，以模仿手动淋巴引流技术的方式设计。该技术可能会增强当前的治疗临床方式，并扩展到家庭疗法。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子优点和更广泛的影响评估标准通过评估来支持的。