New Frontiers in Organic Exciplexes

有机激基复合物的新领域

• 批准号: 2154827
• 负责人: Joseph Dinnocenzo
• 金额: $ 52.5万
• 依托单位: University of Rochester
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2154827&HistoricalAwards=false
• 关键词: New; Frontiers; Organic; Exciplexes

With support from the Chemical Structure, Dynamics and Mechanisms-B Program of the Chemistry Division, Professor Joseph Dinnocenzo at the University of Rochester will investigate new classes of excited state intermediates called exciplexes. Exciplexes form when a molecule which has absorbed light forms a complex with another molecule which is still in its ground state. Exciplexes have found use in a wide variety of applications, such as sensors, biological probes, and in organic light emitting diodes (OLED). Due to their greater solubility in water, the new exciplexes formed from charged electron acceptors and/or donors have much greater potential to find use in biological imaging applications than conventional exciplexes. The fundamental knowledge generated by the proposed research could be used to rationally guide the use of the new exciplexes in these and other applications. Research in this project has the potential to generate new foundational knowledge about exciplexes that could contribute to applications in chemistry, biology, and medicine. Based on connections the PI has established at the University of Guam (UoG), a minority institution, the project will engage undergraduates from the UoG, who are underrepresented in STEM (science, technology, engineering and mathematics) in summer research opportunities.Research into emissive exciplexes with different charge types (cationic, anionic, and nonionic) will extend organic exciplexes in new directions, including those that absorb in the visible region of the electromagnetic spectrum to increase their potential utility. Studies to better understand the fundamental photophysical properties of these exciplex intermediates will likely provide insight into the factors that govern their fate (return electron transfer, radiative and nonradiative decay, separation, etc.). This, in turn, would provide valuable knowledge for the design of new exciplexes that have a variety of potential uses, especially for sensing. The discovery of nonionic exciplexes is particularly intriguing because their emission spectra are expected to be largely independent of medium polarity, which would be an unprecedented result for exciplex emissions and one that could be of practical importance. Research objectives for each of the three types of exciplexes include determining which electron acceptor/donor pairs are optimal for emission, the electronic nature of the exciplexes (e.g. electronic coupling matrix elements) through theoretical fitting of the radiative lifetimes of the exciplexes (determined by Time-Correlated Single Photon Counting, TCSPC) and their fluorescence spectra, measuring some of their photophysical properties (e.g. lifetimes and emission quantum yields), examining the exciplex emissions in a variety of media, and using the combined insights from these studies to synthesize intramolecular examples, which have the greatest potential for practical applications.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学部门的化学结构，动力学和机制-B计划的支持下，罗切斯特大学的约瑟夫·迪诺科佐教授将研究称为Expiplexes的新的激发状态中间体。当吸收光的分子与仍处于基态的另一个分子形成复合物时，分子会形成。 在多种应用中发现了Exoplexes，例如传感器，生物探针和有机光发射二极管（OLED）。由于它们在水中的溶解度较大，与传统的分解相比，由带电电子受体和/或捐赠者形成的新动态具有在生物成像应用中使用的可能性要大得多。拟议的研究产生的基本知识可用于合理地指导在这些应用和其他应用中使用新的分解。该项目中的研究有可能产生有关动态的新基础知识，这些知识可能有助于化学，生物学和医学。基于与少数族裔机构的PI建立的PI建立，该项目将与UOG的本科生互动，UOG的本科生在STEM（科学，技术，技术，工程学）中的代表性不足（夏季研究机会）。在夏季研究机会中，对这些型号的培训类型（catation，catation，divecation，dicrive intrive intrectip）进行了研究。电磁频谱的可见区域以增加其潜在效用。为了更好地了解这些Exciplex中间体的基本光物理特性的研究可能会洞悉控制其命运的因素（回报电子转移，辐射性和非辐射性衰减，分离等）。反过来，这将为设计具有多种潜在用途的新移动物质提供宝贵的知识，尤其是用于感测。非离子动力学的发现特别有趣，因为预计它们的发射光谱将在很大程度上独立于中度极性，这将是发射发射的前所未有的结果，并且可能具有实际重要性。三种类型的分解物中每一种的研究目标包括确定哪些电子受体/供体对发射最佳，通过理论拟合辐射效率的辐射寿命（例如，通过摄影效率来确定其摄影范围的辐射效率），以及他们的摄影范围的辐射效率，以及他们的t摄影频率，以及他们的摄影范围，以及他们的t clotic proctrace intopcctrace and fulore prockection，确定了剥离的电子性质（例如，电子耦合矩阵元素），并确定。 （例如，寿命和排放量量产率），检查各种媒体中的分离排放，并利用这些研究中的组合见解来合成分子内示例，这些示例具有实际应用的最大潜力。该奖项反映了NSF的法定任务，并通过评估了基金会的范围来反映出与基金会的构成相同的支持，并已被评估和宽广的构成。