CAREER: Reliable and Secure Minimally Invasive Bioelectronic Implants through Contextual Awareness

职业：通过情境意识实现可靠、安全的微创生物电子植入

• 批准号: 2146476
• 负责人: Kaiyuan Yang
• 金额: $ 50万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-01 至 2027-04-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2146476&HistoricalAwards=false
• 关键词: CAREER; Reliable; Secure; Minimally; Invasive

Wireless, Battery-less, Minimally Invasive (WBMI) bioelectronics promise a plethora of transformative clinical and scientific applications benefiting human health and well-being. This CAREER project aims at studying and addressing the critical but largely overlooked reliability and security challenges in WBMI bioelectronic devices. Given the extreme power and size constraints of these devices, reliability and security protections cannot be an afterthought and must be designed holistically with the essential bioelectronic functionalities. This project will investigate and create theoretical foundations along with practical hardware and system implementations to tackle three critical challenges towards reliable and secure WBMI bioelectronic implants. The challenges include safe, efficient, and reliable wireless power transfer, secure access and communication in both remote telemedicine and emergency scenarios, and real-time monitoring of potential failures or attacks over extended periods of operation. The research outcome of this project will be a one-of-a-kind hardware platform that expedites the research and development of practically reliable and secure implantable bioelectronic systems for pre-clinical and clinical applications. Meanwhile, this project targets reinforcing the semiconductor hardware workforce by engaging and educating graduate, college, and high school students, especially the underrepresented minorities. This highly interdisciplinary project spanning materials, integrated circuits, power electronics, security, wireless communication, and computing, targets promoting interests in semiconductor and hardware, by engaging students at all levels in high-quality scientific and engineering research activities and creating educational materials to reach a much broader group of K-12 students and the public. This project will investigate principled and proactive methods to enable reliable and secure Wireless, Battery-less, Minimally Invasive (WBMI) bioelectronic implants. The key idea is to exploit positional and contextual awareness of the device to build reliability and security assurances within the fundamental power, communication, and control mechanisms. The research tasks include (1) safe, efficient, and misalignment-tolerant wireless power transfer to WBMI implants, (2) WBMI-specific secure authentication scheme for remote telemedicine and its lightweight implementation, and secure access and communication channel in emergency scenarios, and (3) novel specification-based online monitoring for the bioelectronic implants and transmitters and its efficient, compact hardware implementations. This project involves designing, optimizing, and prototyping energy-efficient miniature circuits and systems that blur traditional design boundaries to realize proactive protections with low overheads. Proof-of-principle implants integrating all the reliability and security protections studied in this project will be fabricated and experimentally evaluated.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

无线，无电池，微创（WBMI）生物电子学有望有多种受益于人类健康和福祉的变革性临床和科学应用。该职业项目旨在研究和解决WBMI生物电子设备中的关键但很大程度上被忽视的可靠性和安全挑战。鉴于这些设备的极端功率和大小约束，可靠性和安全保护不能是事后的想法，并且必须通过基本的生物电子功能进行整体设计。该项目将调查并创建理论基础以及实用的硬件和系统实施，以应对可靠和安全的WBMI生物电子植入物的三个关键挑战。挑战包括安全，高效且可靠的无线功率传输，在远程远程医疗和紧急情况下的安全访问和通信以及对潜在故障或长时间操作中的潜在故障或攻击的实时监控。该项目的研究结果将是一个独一无二的硬件平台，可以加快用于临床前和临床应用的实际可靠且可靠的可靠植入生物电子系统的研究和开发。同时，该项目针对的是通过参与和教育毕业生，大学和高中生，尤其是人数不足的少数群体来增强半导体硬件劳动力。通过使各级的学生参与高质量的科学和工程研究活动，并创建教育材料以吸引更广泛的K-12学生和公众，这项跨学科项目跨越了材料，综合电路，电源，安全性，无线通信和计算，以促进半导体和硬件的兴趣。该项目将研究有原则和主动的方法，以实现可靠且安全的无线，无电池，微创（WBMI）生物电子植入物。关键思想是利用设备的位置和上下文意识，以在基本权力，通信和控制机制内建立可靠性和安全保证。研究任务包括（1）安全，高效和不耐受的无线电源传输到WBMI植入物，（2）WBMI特定的特定特定的安全身份验证方案，用于远程远程医疗及其轻巧的实现，以及紧急情况下的安全访问和通信渠道，以及（3）基于新颖的在线型在线监控器，以实现强大的实现良好的实施和构成效果和效率。该项目涉及设计，优化和原型制作节能的微型电路和系统，这些电路和系统模糊了传统的设计边界，以实现低开销的主动保护。原理植入物整合了该项目中研究的所有可靠性和安全保护措施，将进行制作和实验评估。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子和更广泛影响的评估评估标准来通过评估来获得支持的。

项目成果

ASCH-PUF: A “Zero” Bit Error Rate CMOS Physically Unclonable Function With Dual-Mode Low-Cost Stabilization

ASCH-PUF：具有双模低成本稳定功能的“零误码率 CMOS 物理不可克隆功能”

• DOI: 10.1109/jssc.2022.3233373
• 发表时间: 2023
• 期刊: IEEE Journal of Solid-State Circuits
• 影响因子: 5.4
• 作者: He, Yan;Li, Dai;Yu, Zhanghao;Yang, Kaiyuan
• 通讯作者: Yang, Kaiyuan