CAREER: Establishing a Knowledge Base for Use and Discharge of Poly- and Perfluoroalkyl Substances

事业：建立多氟烷基物质和全氟烷基物质的使用和排放知识库

• 批准号: 2144550
• 负责人: Daqian Jiang
• 金额: $ 52.47万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2144550&HistoricalAwards=false
• 关键词: CAREER; Establishing; Knowledge; Base; Use

Per- and polyfluoroalkyl substances (PFAS) are fluorinated organic chemicals that have been used in numerous consumer products and industrial applications since the 1940s. PFAS are one of the most stable chemicals ever produced. During the last two decades, increasing detection of PFAS in environmental media (including air, water, soils, and biota) has raised significant concerns about their persistence, stability, and adverse impact in the environment including toxicity to living organisms and humans. A critical challenge in the management and mitigation of PFAS contamination in the United States (US) is the lack of curated data and systematic knowledge on the flows, emissions, and discharges of PFAS over their entire manufacturing, supply chain, and product life cycles. The overarching goal of this CAREER project is to develop and validate system analysis and modeling tools that could be used to 1) estimate the total use, accumulation, and discharge of PFAS in the US and 2) help identify the Nation’s geographic hotspots and economic drivers of PFAS contamination. To advance this goal, the Principal Investigator proposes to carry out an integrated data collection and modeling research program structured around two thrusts. Thrust 1 will collect and synthesize available measurements of PFAS uses and emissions (including spatial and temporal data) into a national material flow analysis to generate an integrated data set that can inform and improve PFAS risk assessment and management. Thrust 2 will operationalize multi-disciplinary techniques to guide the safer management of PFAS including the evaluation of the supply-chain and socio-economic drivers of PFAS utilization and consumption in the US. The successful completion of this project will benefit society through the development and validation of new system analysis and modeling tools to guide and support the development and implementation of more effective PFAS risk assessment, management, and mitigation strategies in the US. Additional benefits to society will be achieved through outreach and educational activities including the mentoring of a post-doctorate research fellow, a graduate student, and an undergraduate student at the University of Alabama Tuscaloosa.In the United States (US), various programs, policies, and regulations, ranging from product phaseout to new drinking water health advisories, are currently being developed to manage and mitigate the risks of PFAS contamination to human and ecosystem health. However, the effectiveness of these measures cannot be assessed accurately due to critical knowledge gaps including a lack of system-level knowledge and spatially integrated information about PFAS usages, emissions, and discharges throughout the entire product life cycles. This CAREER project will address these knowledge gaps. The specific objectives of the research are to develop and validate system analysis and modeling tools to: 1) Quantify system-wide use, accumulation, emissions, and discharge of PFAS based on past and future product usage scenarios; 2) Spatially delineate PFAS accumulation and emissions; 3) Characterize the supply-chain and socio-economic drivers of PFAS use; and 4) Estimate the global sensitivity of PFAS accumulation and emissions to methodological and data uncertainties. The successful completion of this project has the potential for transformative impact through 1) the generation of curated data sets on PFAS usages, emissions, and discharges in the US and 2) the development and validation of system analysis and modeling tools to guide and support PFAS risk management and mitigation programs in the US. To implement the educational and training goals of this CAREER project, the Principal Investigator (PI) proposes to develop and teach a new Industrial Ecology course for senior/graduate students at the University of Alabama (UA) Tuscaloosa. In addition, the PI plans to mentor undergraduate students at UA Tuscaloosa and organize immersive summer workshops on material sustainability research to facilitate exchange, networking, and collaboration between faculty and students from US, Asian, and European academic institutions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

自1940年代以来，多氟烷基物质（PFAS）是众多消费产品和induxia的氟化有机化学物质。对生物和人类的毒品（美国）是缺乏策划的数据和系统的，而PFA在其群体，LY链和产品生命周期上的排放是为了发展验证系统。可以使用的系统分析和建模工具有助于进化国家的地理图形热点和PFA污染的经济学驱动因素，以促进这一目标，主要研究者的倡议是执行围绕两个推力的综合数据收集和建模程序。 PFA和排放量（包括空间和时间数据）的测量为国家材料流量分析，以生成可以为PFASK评估和管理提供信息的集成数据，以指导多学科的技术来指导更安全的托管管理。在美国的supp链和社会经济驱动力中，项目将使社会开发新的系统分析和建模工具，以指导和支持更多的EFAS​​风险评估，管理美国的缓解战略。 Phaseout to New NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW NEW Drinking Water Health ADVISORIES, ARE CURRENTLY BEING Developed to Manage and Mitigate The Risks OFAS Contamination to Human and ECOSYSTEM HEALTH. ER, The EffectIVENESS OF THESE MEASURES CANNOTs D关于PFA的空间信息，并将整个产品生命周期放置。 PFA基于过去和未来的使用情况； 3）d;通过1）生成咖啡因的数据集对PFA的使用情况，Indsharges IND 2）系统分析和建模工具的开发验证，以指导和支持美国职业项目的PFA风险管理计划。首席研究员（PI）建议开发和教授新的工业生态课程，以供阿拉巴马大学的高级/研究生，PI计划，Tomentor本科生在Unualosa上，组织临时夏季的夏季讲习班，以促进交易，网络，网络和网络，和网络和网络来自我们，亚洲和欧洲学术研究所的合作学生NSF'Sflects NSF'Stututory Mission，并通过评估g获得了值得支持的支持。