Collaborative Research: Salmon Stewardship: Mapping a Cultural Keystone and Building Genomics Capacity for Alaska Native Peoples

合作研究：鲑鱼管理：为阿拉斯加原住民绘制文化基石并建设基因组学能力

• 批准号: 2140136
• 负责人: Ripan Malhi
• 金额: $ 84.91万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-15 至 2027-05-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2140136&HistoricalAwards=false
• 关键词: Collaborative; Research; Salmon; Stewardship; Mapping

This community-based project combines Indigenous knowledge with the genomic study of three species of salmon on the Kenai Peninsula. Investigators will generate long-read de novo genomes from salmon remains recovered from archaeological contexts and compare them to genomes of present-day salmon from the same location. Analyses will explore the genomic architecture and evolutionary history of these populations over two thousand years. The genomic work is complemented by anthropological research with Kenaitze Elders, which will document Indigenous ecological knowledge of salmon. This project integrates scientific and Indigenous knowledge to reconstruct the dynamic links between salmon and the Kenaitze people since pre-contact times.This project capitalizes on recent advances in models and methods for analysis of ancient DNA and responds to Alaska Native research and education priorities. Tribal members, students, and post-doctoral fellows will collaborate in the analysis of salmon genomes, while tribal perspectives on salmon and salmon use will be documented through archival research, interviews, surveys, and focus groups. Broader impacts of this work include building local genomics research capacity, training of students and post-doctoral fellows, and enhanced understanding of the interdependence of Indigenous lives and salmon, a cultural keystone for many Alaska Native communities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个基于社区的项目将土著知识与基奈半岛三种鲑鱼的基因组研究相结合。研究人员将从考古环境中恢复鲑鱼的长读基因组，并将其与当今鲑鱼的基因组进行比较。分析将探索两千年来这些人群的基因组建筑和进化史。基因组工作与Kenaitze长老有关人类学研究的补充，这将记录鲑鱼的土著生态知识。该项目将科学和土著知识整合在一起，以重建鲑鱼与Kenaitze人之间的动态联系。该项目利用了对古代DNA分析的模型和方法的最新进展，并回应了阿拉斯加本地研究和教育优先事项。部落成员，学生和博士后研究员将在分析鲑鱼基因组中进行合作，而部落对鲑鱼和鲑鱼使用的看法将通过档案研究，访谈，调查和焦点小组记录。这项工作的更广泛影响包括建立本地基因组学研究能力，对学生的培训和博士后研究员，以及对土著生活和鲑鱼的相互依存的了解，这是许多阿拉斯加本土社区的文化钥匙石。这项奖项反映了NSF的法定任务，并通过使用基金会的智力效果和宽阔的范围来评估支持NSF的法定任务，并具有评估。