Collaborative Research: Electrocatalytic Synthesis of Heterocycles from Biomass-Derived Furanics via Immobilized 1st-Row Transition Metal Catalysts

合作研究：通过固定化第一行过渡金属催化剂从生物质衍生的呋喃中电催化合成杂环化合物

• 批准号: 2102191
• 负责人: De-en Jiang
• 金额: $ 15万
• 依托单位: University of California-Riverside
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2022-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2102191&HistoricalAwards=false
• 关键词: Collaborative; Research; Electrocatalytic; Synthesis; Heterocycles

With the support of the Chemical Catalysis program in the Division of Chemistry, Yujie Sun from the University of Cincinnati and De-en Jiang from the University of California-Riverside are studying the electrocatalytic conversion of biomass-derived compounds to value-added compounds. Biomass is a promising sustainable raw material and biomass valorization continues to attract increasing attention. However, most existing methods for the synthesis of value-added chemical building blocks from biomass are inefficient and not cost-effective compared to those employed in the petrochemical industry. Following the principles of green chemistry, Drs. Sun and Jiang will design and develop kinetically viable and low-cost electrocatalysts for the upgrading of biomass-derived chemicals to value-enhanced heterocyclic compounds. The synergy between the experimental and computational efforts of the two principal investigators is notable and offers potential for improved understanding of the various electrocatalytic processes under study. Dr. Sun has been actively developing a new course in Green Chemistry to offer undergraduates a broad background in sustainable chemical approaches and methods. Dr. Jiang has been developing a Freshman Discovery Seminar entitled “Frontiers in Chemical Research” to chemistry-oriented freshmen. Dr. Jiang is also working closely with the Riverside STEM Academy 15, a Riverside Unified School with a focus on STEM. Both research groups are actively involved in a variety of other outreach programs, such as UC Community Day Open House and UC-Chem Summer Camp at the Cincinnati Museum Center.With the support of the Chemical Catalysis program in the Division of Chemistry, Yujie Sun from the University of Cincinnati and Professor De-en Jiang from the University of California Riverside are developing 1st-row transition metal-based electrocatalysts to synthetically upgrade biomass-derived compounds to value-added heterocyclic compounds. Chemical synthesis from biomass has attracted increasing interest because of its abundant, sustainable, and carbon-neutral nature. Due to the existence of multiple functional groups in biomass-derived intermediate compounds, selective transformations are crucial for the successful upgrading of biomass to targeted chemical systems. Taking advantages of both homogeneous and heterogeneous catalytic strategies, Drs. Sun and Jiang will investigate 1st-row transition metal-based and coordinatively-unsaturated electrocatalysts immobilized on electrodes for the selective transformation of biomass-derived furan-based edicts into heterocyclic compounds of interest. Fundamental knowledge of the electrocatalytic mechanisms involved is expected to evolve out of these studies given the tight integration of theory/computation and experiment in the approach.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

在化学系化学催化项目的支持下，辛辛那提大学的 Yujie Sun 和加州大学河滨分校的 De-en Jiang 正在研究生物质衍生化合物向增值化合物的电催化转化。是一种有前途的可持续原材料，生物质增值继续引起越来越多的关注。然而，与传统的生物质合成增值化学构件相比，大多数现有方法效率低下且不具有成本效益。遵循绿色化学的原则，孙博士和江博士将设计和开发动力学可行且低成本的电催化剂，用于将生物质衍生的化学品升级为增值的杂环化合物。两位主要研究人员的计算工作引人注目，并为加深对所研究的各种电催化过程的理解提供了潜力。孙博士一直在积极开发绿色化学新课程，为本科生提供可持续发展的广泛背景。姜博士一直在为化学方向的新生举办题为“化学研究前沿”的新生探索研讨会。姜博士还与 Riverside STEM Academy 15（一所河滨联合学校）密切合作。两个研究小组都积极参与各种其他外展项目，例如辛辛那提博物馆中心的 UC 社区日开放日和 UC-Chem 夏令营。辛辛那提大学的 Yujie Sun 和加州大学河滨分校的 De-en Jiang 教授正在开发第一排过渡金属基电催化剂，以将生物质衍生的化合物合成升级为增值杂环化合物。由于其丰富、可持续和碳中性的性质而引起了越来越多的关注由于生物质衍生的中间化合物中存在多个官能团，选择性转化对于生物质的成功升级至关重要。 Sun 和 Jiang 博士将利用均相和非均相催化策略，研究固定在电极上的第一排过渡金属和配位不饱和电催化剂，用于将生物质衍生的呋喃基化合物选择性转化为杂环。鉴于理论/计算和实验的紧密结合，相关电催化机制的基础知识有望从这些研究中发展出来。该奖项反映了 NSF 的法定使命，并通过使用基金会的智力价值和更广泛的影响审查标准进行评估，被认为值得支持。