Untersuchungen zur hormonellen Modulation dopaminerger Mechanismen von impulsivem Verhalten (B03)

冲动行为的多巴胺能机制的激素调节研究（B03）

• 批准号: 244721107
• 金额: --
• 依托单位: Max-Planck-Institut für Stoffwechselforschung
• 依托单位国家: 德国
• 项目类别: CRC/Transregios
• 财政年份: 2014
• 资助国家: 德国
• 起止时间: 2013-12-31 至 2017-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/244721107?language=en
• 关键词: Untersuchungen; zur; hormonellen; Modulation; dopaminerger

Building on the achievements of our previous work, the second phase of our project will focus on integrating the various biological factors into circuit models of interactions between homeostatic mechanisms and reward-related signals. These models will combine recent advances in generative modelling of human neuroimaging and behavioural data with genetic, metabolic, endocrine, and immunological analyses during experimental perturbations of homeostasis and reward processing. A focus will be on obtaining compact, tractable indices of network dynamics with regard to homeostatic and affective (hedonic) valence processes that govern food choice in different states of satiety.

在我们先前工作的成就的基础上，我们项目的第二阶段将着重于将各种生物学因素整合到稳态机制和与奖励相关的信号之间的相互作用模型中。这些模型将在实验性稳态和奖励处理过程中，将人类神经影像和行为数据的生成建模与遗传，代谢，内分泌和免疫学分析结合起来。将重点放在获得有关稳态和情感（Hedonic）价值过程中的紧凑，可拖动的网络动力学指标，这些过程控制着不同饱腹感的食物选择。