REU Site: Cellular Bioengineering: From Biomaterials to Stem Cells

REU 网站：细胞生物工程：从生物材料到干细胞

• 批准号: 1950509
• 负责人: David Shreiber
• 金额: $ 42.88万
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1950509&HistoricalAwards=false
• 关键词: REU; Site; Cellular; Bioengineering; Biomaterials

The REU Site: Cellular Bioengineering: From Biomaterials to Stem Cells at Rutgers University-New Brunswick provides unique opportunities to a diverse population of undergraduate students to perform cutting-edge, cross-disciplinary research in the field of Cellular Bioengineering and develop a deeper understanding of graduate level research to accelerate their development as research scientists and engineers. The program includes strategic and impactful formal programming, active mentoring, collaboration, and careful monitoring of the student experience. The site includes a Cellular Bioengineering Boot Camp which introduces Scholars to laboratory and imaging skills that accelerate their integration into their research labs. Exciting research projects that rely heavily on interdisciplinary collaboration introduce the Scholars to a broad array of topics grounded in Cellular Bioengineering. A focus on Innovation and Entrepreneurship parallels the NSF I-Corps initiative for translational research to capitalize on the potential for new technology that emanates from the research. An optional day-long clinical immersion allows the students to engage with clinicians for hands-on experience with current devices and technology. Additionally, this site includes a focus on health disparities to enhance the impact of the comprehensive diversity of the cohorts by increasing our Scholars’ awareness of the disparate impact of biomedical research and eventual treatments on different US communities, including many to which the Scholars belong. Weekly seminars and discussion groups allow tracking and monitoring of the Scholars’ experiences while concurrently developing communication skills, career goals, and other professional skills.The REU Site: Cellular Bioengineering: From Biomaterials to Stem Cells at Rutgers University-New Brunswick provides opportunities to perform cutting-edge, cross-disciplinary research in the field of Cellular Bioengineering to a diverse population of undergraduates. The REU site focuses on recruiting students who traditionally do not have these research opportunities, including under-represented minorities, women, students who are in the first generation in their family to attend college, and students who attend small schools that do not have extensive research enterprises. The REU site provides these students with an immersive, 10-week research experience. Student research project areas include engineering cell therapies, drug delivery, regenerative medicine, cellular imaging, and systems biology. In these areas, students apply engineering principles and problem-solving skills to promote the progress of science to understand basic elements of how cells communicate with one another to perform biological and physiological functions, and to advance national health through design and development approaches to restore these functions in cases of injury and disease. In parallel to these efforts, students participate in weekly professional development seminars and workshops that build on and complement the research activities. These activities promote a deep understanding of the research projects to emphasize that research is much more than what a student does in the laboratory, but also what the big picture problem is that the student is trying to solve, why it is important to solve that problem, and how the research is aimed at solving that problem in a new and innovative way. Students work to communicate their research in writing through preparation of mock fellowships and personal statements and orally through posters and presentations. The REU program provides financial support for the students to deliver these presentations at national meetings. To broaden the students’ appreciation and perspectives for the importance of research, they complete exercises in Innovation & Entrepreneurship and in Health Disparities. The exercises in Innovation & Entrepreneurship enable students to understand how their summer research in cellular bioengineering can be translated to new products and technology and how to identify needs an opportunities that can be addressed by new research and technology and culminate with a mock business pitch. The exercises in Health Disparities aim to inspire students to recognize the disparate impact of biomedical research and eventual treatments on different US communities, including many to which our summer students belong. All of these exercises are designed for students to consider different audiences and stakeholders when communicating their research, which significantly enhances their understanding of the work and stimulates them to identify new opportunities and challenges for future research and technology.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

REU网站：蜂窝生物工程：从生物材料到罗格斯大学新不伦瑞克省的干细胞，为多样化的本科生提供了独特的机会，可以在细胞生物工程领域进行尖端的，跨学科的研究，并对研究生水平的更深入了解，以加快研究生的发展研究，以加快研究科学家和工程师的研究。该计划包括战略性和有影响力的正式编程，积极的指导，协作以及对学生体验的仔细监控。该网站包括一个蜂窝工程新兵训练营，该训练营向实验室和成像技能引入学者，以加速其融入研究实验室。在很大程度上依赖跨学科合作的令人兴奋的研究项目将学者介绍了以蜂窝生物工程为基础的广泛主题。对创新和企业家精神的重点与NSF I-Corps倡议相似，用于翻译研究，以利用从研究中散发出的新技术的潜力。可选的为期一天的临床沉浸，使学生能够与临床医生与当前设备和技术进行动手实践经验。此外，该网站还关注健康差异，以提高学者对生物医学研究和最终对不同社区的不同影响的认识，从而增强同伙的全面多样性的影响，包括许多学者所属的许多社区。 Weekly semianars and discussion groups allow tracking and monitoring of the Scholars’ experiences while concurrently developing communication skills, career goals, and other professional skills.The REU Site: Cellular Bioengineering: From Biomaterials to Stem Cells at Rutgers University-New Brunswick provides opportunities to perform cutting-edge, cross-disciplinary research in the field of Cellular Bioengineering to a diversity population of undergraduates. REU网站的重点是招募传统上没有这些研究机会的学生，包括代表性不足的少数群体，妇女，在家庭中第一代的学生上大学，以及参加没有广泛研究企业的小型学校的学生。 REU网站为这些学生提供了沉浸式10周的研究经验。学生研究项目领域包括工程细胞疗法，药物输送，再生医学，细胞成像和系统生物学。在这些领域，学生采用工程原则和解决问题的技能来促进科学的进步，以了解细胞如何相互沟通以执行生物学和身体功能的基本要素，并通过设计和发展方法来促进国家健康，以在伤害和疾病的情况下恢复这些功能。与这些努力同时，学生参加了每周的专业发展半手赛和讲习班，以基于研究活动并完成研究活动。这些活动促进了对研究项目的深刻了解，以强调研究比学生在实验室中所做的要多得多，而且大幅度的问题是学生正在尝试解决该问题，为什么要解决该问题很重要，以及如何以一种新的和创新的方式解决该问题。学生通过准备模拟奖学金和个人陈述以及通过海报和演讲来以书面形式传达他们的研究。 REU计划为学生提供了在国家会议上进行这些演讲的财政支持。为了扩大学生对研究重要性的赞赏和观点，他们完成了创新和企业家精神和健康差异方面的练习。创新与企业家精神的练习使学生能够了解如何将他们的夏季生物工程研究转化为新产品和技术，以及如何识别新的研究和技术可以解决的机会，并通过模拟商业宣传来解决。健康差异的练习旨在激发学生认识到生物医学研究和最终治疗对不同社区的不同影响，包括我们夏季学生所属的许多社区。所有这些练习都是为了让学生在交流研究时考虑不同的受众和利益相关者的设计，这大大增强了他们对工作的理解，并刺激了他们，以确定未来的研究和技术的新机会和挑战。该奖项反映了NSF的法定任务，并通过使用该基金会的智力功能和广泛的影响来评估CRITERIA，并通过评估来评估。

项目成果

Cerebrospinal fluid replacement solutions promote neuroglia migratory behaviors and spinal explant outgrowth in microfluidic culture

• DOI: 10.1002/term.3164
• 发表时间: 2020-12-15
• 期刊: JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
• 影响因子: 3.3
• 作者: Cliver, Richard N.;Ayers, Brian;Vazquez, Maribel
• 通讯作者: Vazquez, Maribel

The Use of Collagen Methacrylate in Actuating Polyethylene Glycol Diacrylate–Acrylic Acid Scaffolds for Muscle Regeneration

• DOI: 10.1007/s10439-023-03139-8
• 发表时间: 2023-02
• 期刊: Annals of Biomedical Engineering
• 影响因子: 3.8
• 作者: Yoliem S Miranda Alarcón;D. Jazwinska;Terrence Lymon;A. Khalili;D. Browe;Brandon Newton;M. Pellegrini;Rick I Cohen;D. Shreiber;J. Freeman