MRI: Acquisition of a Variable-Temperature, Dual-Wavelength, Single-Crystal X-Ray Diffractometer

MRI：获取变温、双波长、单晶 X 射线衍射仪

基本信息

批准号：
1828117
负责人：
Leonard MacGillivray
金额：
$ 27.97万
依托单位：
University of Iowa
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-01 至 2021-07-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828117&HistoricalAwards=false
关键词：
MRI Acquisition Variable Temperature Dual

项目摘要

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation programs. Professor Leonard MacGillivray from University of Iowa and colleagues James Gloer, Christopher Pigge, Gregory Friestad and Scott Daly have acquired a dual source single crystal diffractometer. In general, an X-ray diffractometer allows accurate and precise measurements of the full three-dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here impact many areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research and research training of graduate and undergraduate students in chemistry, medicinal chemistry, pharmacy and biochemistry at this institution. It also provides crystallographic services free of charge to faculty and student researchers in primarily undergraduate institutions that do not possess single-crystal X-ray diffractometers in eastern Iowa, western Illinois, and northern Missouri.The proposal is aimed at enhancing research and education at all levels. It especially impacts studies on effects of noncovalent bonding in molecular solids and exploration of templated solid-state reactions. The diffractometer aids the characterization of synthesized compounds using non-innocent ligands, and those having soft-donor ligands with f-elements. The instrument is essential for studies coupling earth-abundant metals with non-innocent ligands to be used in electrochemical carbon dioxide reduction. It is also useful in designing catalytic carbon-hydrogen activation with N-acylhydrazones and for studying reactivity and selectivity in radical polar crossover reactions.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项得到了主要的研究工具和化学研究工具计划的支持。来自爱荷华大学的伦纳德·麦吉利夫里（Leonard MacGillivray）教授和同事詹姆斯·格洛尔（James Gloer），克里斯托弗·皮格（Christopher Pigge），格雷戈里·弗里斯塔德（Gregory Friestad）和斯科特·戴利（Scott Daly）获得了双源单晶衍射仪。通常，X射线衍射仪可以准确，精确地测量分子的完整三维结构，包括键距离和角度，并提供有关分子相对于相邻分子的空间排列的准确信息。这里描述的研究影响了许多领域，包括有机和无机化学，材料化学和生物化学。该工具是该机构化学，药物化学，药房和生物化学的研究生和本科生的教学和研究培训的组成部分。它还为主要是本科机构的教职员工和学生研究人员免费提供晶体学服务水平。它特别影响了对非共价键在分子固体中的影响的研究和模板固态反应的探索。衍射仪使用非纯配体有助于合成化合物的表征，以及具有F-元素的软分配体的化合物。该仪器对于将含有地球丰富金属与非生物配体耦合的研究至关重要，该金属用于电化学二氧化碳还原。它也可用于使用N-酰基氢酮设计催化碳 - 氢激活，并在根本极性跨界反应中研究反应性和选择性。该奖项反映了NSF的法定任务，并被认为是值得通过基金会的知识分子和更广泛的影响来通过评估来支持的。审查标准。