Training workshop on genomic methods and analysis for early-career invertebrate systematists

为早期职业无脊椎动物系统学家举办的基因组方法和分析培训研讨会

• 批准号: 1826662
• 负责人: Heather Bracken-Grissom
• 金额: $ 1.92万
• 依托单位: Florida International University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1826662&HistoricalAwards=false
• 关键词: Training; workshop; genomic; methods; analysis

Invertebrates represent 95% of animal diversity, yet few genomic resources exist for the group, leaving a great deal of information on gene diversity and function to be discovered. Coordination among limited research efforts is lacking, limiting comparability among projects and in some cases resulting in duplicated efforts. The Global Invertebrate Genomics Alliance (GIGA) is a network of diverse scientists working to coordinate and advance invertebrate research using advanced techniques to shed light on this genomic diversity and guide scientific discoveries. This workshop, hosted at the 3rd bi-annual GlGA Conference, will provide a much-needed training opportunity for graduate students and early-career researchears in the latest cutting-edge approaches for comparative genomics and bioinformatics in systematic biology. The workshop will also get participants actively involved with developing best practices in invertebrate genomics. Workshop participants will be recruited from diverse levels of expertise with a specific effort to target underrepresented minorities. Information from this workshop will be shared with students and the community at large through publicly available learning exercises and tutorials, facilitating information access to minority groups. Material from this workshop will also be showcased through several media outlets to emphasize the link and importance of invertebrate animals to society as well as the power of genomics in studying marine resources and habitats.The few invertebrate genomes that have been fully sequenced reveal major structural differences with vertebrates, unusual frequencies of transposable elements and genomic innovations among other features. Presently, research coordination among scientists carrying out non-model invertebrate genomics research remains sparse or scattered. Additionally, as a whole, the invertebrate systematics community is inadequately trained to work broadly at the genomic level, thus hampering progress elucidating the evolutionary history for most of the life on earth. This workshop will work to position invertebrate systematists at the leading edge of phylogenomics methodology and begin the process of catching up to their vertebrate systematics counterparts. Primary objectives of this workshop are to 1) provide bioinformatics training and support to the community; 2) promote the sharing of data, resources, and future collaborations; 3) disseminate knowledge on the best practices for laboratory protocols and techniques; and 4) inform and support student researchers in the field of invertebrate genomics.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

无脊椎动物占动物多样性的95％，但该小组的基因组资源很少，留下了有关基因多样性和功能的大量信息。缺乏有限的研究工作之间的协调，限制了项目之间的可比性，在某些情况下导致了重复的努力。全球无脊椎动物基因组学联盟（GIGA）是一个多元化的科学家网络，旨在使用先进的技术来协调和推进无脊椎动物研究，以阐明这种基因组多样性并指导科学发现。该研讨会在第三届双年度GLGA会议上举办，将为研究生和早期的研究人员提供急需的培训机会，以用于系统生物学的比较基因组学和生物信息学的最新尖端方法。该研讨会还将使参与者积极参与发展无脊椎动物基因组学的最佳实践。研讨会参与者将从各种专业知识中招募，以针对代表性不足的少数民族的特定努力。该研讨会的信息将通过公开可用的学习练习和教程与学生和社区共享，从而促进信息访问少数群体。该研讨会的材料也将通过几个媒体展示，以强调无脊椎动物与社会的联系和重要性以及基因组学在研究海洋资源和栖息地中的力量。几乎没有脊椎动物基因组已完全测序的无脊椎动物基因组揭示了与脊椎动物，不属性元素的主要结构差异，其中包括不良元素和基因组成的元素。目前，进行非模型无脊椎动物基因组学研究的科学家之间的研究协调仍然很少或分散。此外，总体而言，无脊椎动物系统社区的培训不足，无法在基因组水平上进行广泛的工作，从而阻碍了阐明地球上大部分生命的进化史的进步。该研讨会将致力于将无脊椎动物系统主义者定位在系统基因学方法论的前沿，并开始赶上其脊椎动物系统的过程。该研讨会的主要目标是1）为社区提供生物信息学培训和支持； 2）促进数据，资源和未来合作的共享； 3）传播有关实验室协议和技术最佳实践的知识； 4）为无脊椎动物基因组学领域的学生研究人员提供信息和支持。该奖项反映了NSF的法定任务，并使用基金会的知识分子优点和更广泛的影响评估标准，被视为值得通过评估来获得支持。